User profiles for S. Bahram

Seiamak Bahram

Professor of Medicine (Immunology), University of Strasbourg, France
Verified email at unistra.fr
Cited by 16372

MIC genes: from genetics to biology

S Bahram - Advances in immunology, 2001 - Elsevier
The specific interaction between the α/β T cell receptor (TCR) and a peptide-bound major
histocompatibility complex (MHC) molecule triggers the adaptive immune response (Garboczi …

Genetics, genomics, and evolutionary biology of NKG 2D ligands

R Carapito, S Bahram - Immunological reviews, 2015 - Wiley Online Library
… Here, we review the molecular diversity of NKG 2 DL s, discuss the increasing appreciation
… force(s) that seem to drive the multiplicity and diversity of NKG 2 DL s while maintaining their …

Cell stress-regulated human major histocompatibility complex class I gene expressed in gastrointestinal epithelium.

V Groh, S Bahram, S Bauer… - Proceedings of the …, 1996 - National Acad Sciences
S. Bahram received support from the Association pour la Recherche sur la Polyarthrite. S.
Bauer is supported by the Deutsche Forschungsgemeinschaft. This work was supported by …

Selection of evolutionarily conserved mucosal-associated invariant T cells by MR1

E Treiner, L Duban, S Bahram, M Radosavljevic… - Nature, 2003 - nature.com
… Regardless, the strict conservation of both MR1 and MAIT cells among mammalian
species implies stringent evolutionary pressure for the function(s) fulfilled by MAIT cells. …

[PDF][PDF] A direct role for NKG2D/MICA interaction in villous atrophy during celiac disease

…, S Bahram, N Cerf-Bensussan, S Caillat-Zucman - Immunity, 2004 - cell.com
… Interestingly, one subclone of this patient’s cell line lost surface NKG2D expression. Both
redirected lysis of P815 cells and cell-… This work was supported by INSERM (Ré seau Progre` s

A second lineage of mammalian major histocompatibility complex class I genes.

S Bahram, M Bresnahan… - Proceedings of the …, 1994 - National Acad Sciences
Major histocompatibility complex (MHC) class I genes typically encode polymorphic peptide-binding
chains which are ubiquitously expressed and mediate the recognition of …

Back to the future: bacteriophages as promising therapeutic tools

P Domingo‐Calap, P Georgel, S Bahram - Hla, 2016 - Wiley Online Library
Bacteriophages (phages), natural predators of bacteria, are becoming increasingly attractive
in medical and pharmaceutical applications. After their discovery almost a century ago, they …

Genome-wide association studies identify IL23R-IL12RB2 and IL10 as Behçet's disease susceptibility loci

…, Y Horie, M Takeno, S Sugita, M Mochizuki, S Bahram… - Nature …, 2010 - nature.com
Behçet's disease is a chronic systemic inflammatory disorder characterized by four major
manifestations: recurrent ocular symptoms, oral and genital ulcers and skin lesions 1 . We …

Triplet repeat polymorphism in the transmembrane region of the MICA gene: a strong association of six GCT repetitions with Behcet disease

…, K Goto, S Nakamura, S Bahram… - Proceedings of the …, 1997 - National Acad Sciences
… using the Applied Biosystems PRISM dye terminator cycle sequencing ready reaction kit
with AmpliTaq DNA polymerase, FS (Perkin–Elmer/Cetus) according to the manufacture’s

Identification of driver genes for critical forms of COVID-19 in a deeply phenotyped young patient cohort

…, C Moog, TW Chittenden, S Bahram - Science translational …, 2022 - science.org
… The qRT-PCR protocol consisted of 95C for 2 min followed by 40 cycles of 95C for 5 s and
60C for 30 s. All reactions were performed in duplicate, and the relative amounts of transcripts …