New technologies enabling genome-wide interrogation have led to a large and rapidly growing
number of autism spectrum disorder (ASD) candidate genes. Although encouraging, the …

DNA mismatch repair is important because of its role in maintaining genomic integrity and
its association with hereditary non-polyposis colon cancer (HNPCC). To identify new human …

… To the best of our knowledge, this is the first example of an integrated gene database for a
… Conflict of interest statement: MindSpec and Sharmila Banerjee-Basu hold the license for …

… The first is of AS, and the second is of autistic traits in the general population. AS is marked
by social and behavioral impairments, but is not associated with language delay during …

Despite the biomedical advances of the last century, infectious diseases remain a leading
cause of mortality and morbidity, particularly within the developing world (Fig. 1)(World Health …

… A well-studied member of this class, CSX, is expressed only in the heart and is critical for
cardiogenensis (49). Targeted disruption of the mouse homolog of CSX causes early …

… We believe that this is the first description of a human disorder caused by mutations … In the
group II chaperonin family, this domain is responsible for ATP hydrolysis and the substitution is …

Congenital heart defects (CHDs) are among the most common birth defects in humans (incidence
8–10 per 1,000 live births). Although their etiology is often poorly understood, most are …

While prenatal maternal infection has received attention as a preventable and treatable risk
factor for autism, findings have been inconsistent. This paper presents the results of a meta‐…

… It would appear, therefore, that, while the I87M FOXC1 variant is being introduced into cells,
mRNA is being produced, and the protein machinery of the cell is competent to synthesize …