Leucine-rich repeat kinase 2 (LRRK2), a complex kinase/GTPase mutated in Parkinson's
disease, has been shown to physically and functionally interact with cytoskeletal-related …

Dopamine dyshomeostasis has been acknowledged among the determinants of nigrostriatal
neuron degeneration in Parkinson’s disease (PD). Several studies in experimental models …

This study is based on 30-year long simulations of the wind-wave field in the Mediterranean
Sea carried out with the WAM model. Wave fields have been computed for the 2071–2100 …

… ) as well as educational and training on the topic in question ( 10 10 Corrêa SR, Mazuko C,
Mitchell G, Pastrana T, Lima L, Murray S. Identificando pacientes para cuidados paliativos na …

… Given that the most common Parkinson’s disease LRRK2 G2019S mutation displays
increased kinase activity, our results suggest that mutant LRRK2 may impair synaptic vesicle …

Mutations in LRRK2 gene cause inherited Parkinson's disease (PD) and variations around
LRRK2 act as risk factor for disease. Similar to sporadic disease, LRRK2-linked cases show …

Leucine-rich repeat kinase 2 (LRRK2) is a kinase involved in different cellular functions,
including autophagy, endolysosomal pathways, and immune function. Mutations in LRRK2 …

Over the last two decades, a number of studies have underlined the importance of lysosomal‐based
degradative pathways in maintaining the homeostasis of post‐mitotic cells, and …

… a 10 s … s TDMA-Ti precursor and purge of 5 s high-purity N 2 purge with a flow rate of 20
sccm, while the second step consisted of a pulse of 0.015 s H 2 O precursor and a purge of 5 s …

Eradication of implant centered infection remains a clinical challenge as the biofilm formation
protects the bacteria. Bactericidal surfaces represent an effective tool in the prevention of …