… Despite representing slightly more than 2% of adult body weight, the human brain accounts
for 20% of the body’s total energy requirement 8 . The brain’s main competitors for energy …

Lower brain glucose metabolism is present before the onset of clinically measurable cognitive
decline in two groups of people at risk of Alzheimer’s disease---carriers of apolipoprotein …

Blood levels of polyunsaturated fatty acids (PUFA) are considered biomarkers of status.
Alpha-linolenic acid, ALA, the plant omega-3, is the dietary precursor for the long-chain omega-3 …

Although high α-linolenic acid flaxseed (Linum usitatissitmum) is one of the richest dietary
sources of α- linolenic acid and is also a good source of soluble fibre mucilage, it is relatively …

… Δ 6 desaturase that would supposedly restrain ALA’s conversion would be bypassed, but this
… (stearic acid) to three double bonds (ALA; Cunnane 2003a), the fourth double bond in SDA …

We studied the effect of increasing the frequency of meals on serum lipid concentrations and
carbohydrate tolerance in normal subjects. Seven men were assigned in random order to …

There is considerable interest in the impact of (n-3) long-chain PUFA in mitigating the morbidity
and mortality caused by chronic diseases. In 2002, the Institute of Medicine concluded …

The objective was to determine the influence of consuming 50 g flaxseed/d for 4 wk on
several indexes of nutrition in young healthy adults. During flaxseed consumption, alpha-…

The African savanna ecosystem of the large mammals and primates was associated with a
dramatic decline in relative brain capacity associated with little docosahexaenoic acid (DHA), …

Cognitive decline in the elderly, particularly Alzheimer’s disease (AD), is a major socio-economic
and healthcare concern. We review here the literature on one specific aspect of diet …