Cerebral malaria claims more than 1 million lives per year. We report that heme oxygenase-1
(HO-1, encoded by Hmox1) prevents the development of experimental cerebral malaria (…

In regions of high rates of malaria transmission, mosquitoes repeatedly transmit liver-tropic
Plasmodium sporozoites to individuals who already have blood-stage parasitemia 1 . This …

… for SR-BI’s role in infection. First, with regard to SR-BI’s observed role in the invasion step,
we have hypothesized that SR-BI might mediate the sporozoite’s initial binding and entry into …

… The reintroduction of freshwater shrimp – a predator of Biomphalaria, vector of S. mansoni
– can reduce the number of infected snails and reinfection rates, which, when combined with …

The clinically silent Plasmodium liver stage is an obligatory step in the establishment of
malaria infection and disease. We report here that expression of heme oxygenase-1 (HO-1, …

The spectrum of the clinical presentation and severity of malaria infections is broad, ranging
from uncomplicated febrile illness to severe forms of disease such as cerebral malaria (CM), …

Malaria causes more than 1 million deaths every year with cerebral malaria (CM) being a
major cause of death in Sub-Saharan African children. The nature of the malaria-associated …

… , CCC is presently understood as an expression of the host’s incapacity to totally eliminate
the heart parasitism, a particularity of the host’s failure to eradicate T. cruzi from the organism. …

Malaria remains one of the greatest burdens to global health, causing nearly 500,000
deaths in 2014. When manifesting in the lungs, severe malaria causes acute lung injury/acute …

Clinical information was available for 32 of 33 New World primates with fatal toxoplasmosis,
all of which were subjected to a variable number of pathological observations. Death without …