… Crucially, the exonuclease treatment revealed TSS by means of a characteristic redistribution
of a gene’s cDNAs towards a sawtooth-like profile with an elevated sharp 5′ flank. For …

… Thereby, Proteinortho's clustering algorithm becomes more stringent with increasing values
of in splitting in particular large groups. While these groups are left intact for , thresholds of …

… Synthetic riboswitches based on artificial aptamers are particularly valuable gadgets because
they can respond to ligands that are orthogonal to the host organism’s native metabolites …

… Put in simple terms, the score <s> is the average score over all possible pairs weighted by
… We can use this expected score <s> to normalize our observed scores s arriving at the final …

… Green fluorescent protein (GFP) emission was measured in Sorensen’s phosphate buffer
(pH 8.0) at 509 nm with excitation wavelength of 488 nm. Fluorescence intensity was …

… The methods utilize a wide variety of different properties and features of the nucleotide
sequence, the predicted translation product(s), and in some case also of the transcript’s RNA …

Comparative analysis of multiple genomes in a phylogenetic framework dramatically improves
the precision and sensitivity of evolutionary inference, producing more robust results than …

… We used fixed-length intervals of size l to determine λ r = s r /l from the number of read starts
s r in the region r. The parameter λ ave models the average genome wide arrival rate of read …

RNAz is a widely used software package for de novo detection of structured noncoding RNAs
in comparative genomics data. Four years of experience have not only demonstrated the …

Riboswitches have gained attention as tools for synthetic biology, since they enable researchers
to reprogram cells to sense and respond to exogenous molecules. In vitro evolutionary …