The central executioner of apoptosis: multiple connections between protease activation and mitochondria in Fas/APO-1/CD95-and ceramide-induced apoptosis

…, M Castedo, E Daugas, HG Wang, S Geley… - The Journal of …, 1997 - rupress.org
… After stabilization of the adsorption during a minimum interval of 30 s, the indicated
substance was added in a volume of 5 μl. The loss of absorption induced by 5 mM atrectyloside …

Caspase-2 at a glance

LL Fava, FJ Bock, S Geley… - Journal of cell …, 2012 - journals.biologists.com
… Stephan Geley … Bock, Stephan Geley, Andreas Villunger; Caspase-2 at a glance. J
Cell Sci 15 December 2012; 125 (24): 5911–5915. doi: https://doi.org/10.1242/jcs.115105 …

Anaphase-promoting complex/cyclosome–dependent proteolysis of human cyclin A starts at the beginning of mitosis and is not subject to the spindle assembly …

S Geley, E Kramer, C Gieffers, J Gannon… - The Journal of cell …, 2001 - rupress.org
… is a relatively stable protein during S and G2 phase, but becomes … In cells arrested in S phase
with hydroxyurea, the levels of … stable protein during S and G2 phase of proliferating cells. …

RNAi: ancient mechanism with a promising future

S Geley, C Müller - Experimental gerontology, 2004 - Elsevier
S. pombe has one member of the Argonaute family, a Dicer homologue and a gene with
potential RDRP activity. Disruption of any of these genes resulted in a loss of heterochromatin …

Prostate-specific membrane antigen expression in the neovasculature of gastric and colorectal cancers

…, D Öfner, B Zelger, C Ensinger, XJ Yang, S Geley… - Human pathology, 2009 - Elsevier
Prostate-specific membrane antigen (PSMA), a type II transmembrane metallo-peptidase
highly overexpressed in prostate cancer cells, has been studied as a targeting molecule in …

Orphan kinases turn eccentric: a new class of cyclin Y-activated, membrane-targeted CDKs

P Mikolcevic, J Rainer, S Geley - Cell Cycle, 2012 - Taylor & Francis
PCTAIRE kinases (PCTK) are a highly conserved, but poorly characterized, subgroup of
cyclin-dependent kinases (CDK). They are characterized by a conserved catalytic domain …

p14–MP1-MEK1 signaling regulates endosomal traffic and cellular proliferation during tissue homeostasis

…, M Offterdinger, A Villunger, S Geley… - The Journal of cell …, 2006 - rupress.org
… To detect keratinocytes in S phase, pregnant animals at 18.5 d of gestation were injected
with BrdU. 1 h later, embryonic skin was collected and analyzed by immunofluorescence …

[PDF][PDF] Simultaneous detection of multiple green fluorescent proteins in live cells by fluorescence lifetime imaging microscopy

R Pepperkok, A Squire, S Geley, PIH Bastiaens - Current Biology, 1999 - cell.com
The green fluorescent protein (GFP) has proven to be an excellent fluorescent marker for
protein expression and localisation in living cells [1–5]. Several mutant GFPs with distinct …

[HTML][HTML] Identification of glucocorticoid-response genes in children with acute lymphoblastic leukemia

S Schmidt, J Rainer, S Riml, C Ploner, S Jesacher… - Blood, 2006 - Elsevier
… To identify possible common upstream component(s) of the cell death pathway induced
by GCs in childhood ALL, we exploited a comparative expression profiling strategy (Figure 1, …

The PIDDosome activates p53 in response to supernumerary centrosomes

…, L Eiterer, E Demetz, G Weiss, S Geley… - Genes & …, 2017 - genesdev.cshlp.org
… U2OS-Trex-MYC-PLK4 cells were arrested in S phase with thymidine. After 14 h, they were
… S10A) or immunoblot directly during S arrest or released for 24 and 48 h. (B) Scatter plot for …