User profiles for S. Gladson

S.Edwin Gladson

Asso.Professor of Physics, St.Xavier's Catholic College of Engineering, Chunkankadai
Verified email at sxcce.edu.in
Cited by 105

[HTML][HTML] Vildagliptin ameliorates pulmonary fibrosis in lipopolysaccharide-induced lung injury by inhibiting endothelial-to-mesenchymal transition

…, S Gladson, R Nishimura, I Shimomura, S Karasawa… - Respiratory …, 2017 - Springer
… Furthermore, Masson’s trichrome staining of lung sections to evaluate fibrotic lesions
showed that recurrent LPS exposure led to prominent pulmonary fibrosis, and this fibrosis was …

[HTML][HTML] BMPR2 expression is suppressed by signaling through the estrogen receptor

…, C Yu, JA Phillips III, R Gaddipati, S Gladson… - Biology of sex …, 2012 - Springer
… Amplification parameters consisted of initial denaturation at 95C for 10 min followed by 40
cycles of denaturation at 95C for 15 s and annealing and extension at 60C for 1 min. Relative …

Cytoskeletal defects in Bmpr2-associated pulmonary arterial hypertension

…, S Gladson, H Loibner, S Bai… - … of Physiology-Lung …, 2012 - journals.physiology.org
The heritable form of pulmonary arterial hypertension (PAH) is typically caused by a mutation
in bone morphogenic protein receptor type 2 (BMPR2), and mice expressing Bmpr2 …

Estrogen metabolite 16α-hydroxyestrone exacerbates bone morphogenetic protein receptor type II–associated pulmonary arterial hypertension through microRNA-29 …

…, JP Fessel, AR Hemnes, S Gladson, J French, S Shay… - Circulation, 2016 - Am Heart Assoc
Background— Pulmonary arterial hypertension (PAH) is a proliferative disease of the
pulmonary vasculature that preferentially affects women. Estrogens such as the metabolite 16α-…

Endothelial HIF signaling regulates pulmonary fibrosis-associated pulmonary hypertension

…, CS Moore, TR Blackwell, S Gladson… - … of Physiology-Lung …, 2016 - journals.physiology.org
Pulmonary hypertension (PH) complicating chronic parenchymal lung disease, such as
idiopathic pulmonary fibrosis, results in significant morbidity and mortality. Since the hypoxia-…

Magnetic resonance mapping demonstrates benefits of VEGF–induced myocardial angiogenesis

…, ML Chuang, K Harada, JJ Lopez, SR Gladstone… - Nature medicine, 1995 - nature.com
… atrium (RA), right ventricle (RV) and pulmonary artery (PA, frames 1–2), left atrium (LA), left
ventricle (LV), aorta (AO, frames 3–4), then to the normally supplied intraventricular septum (S

Bone marrow–derived cells contribute to the pathogenesis of pulmonary arterial hypertension

…, X Chen, M Talati, BW Nunley, S Gladson… - American Journal of …, 2016 - atsjournals.org
… from the dataset that map to the pathway divided by the total number of molecules that map
to the canonical pathways (indicated by the orange line and boxes), and (2) Fisher’s exact …

[HTML][HTML] The selective angiotensin II type 2 receptor agonist, compound 21, attenuates the progression of lung fibrosis and pulmonary hypertension in an experimental …

…, A Horowitz, K Horton, A Kumar, S Gladson… - Frontiers in …, 2018 - frontiersin.org
… The use, distribution or reproduction in other forums is permitted, provided the original
author(s) and the copyright owner are credited and that the original publication in this journal is …

[HTML][HTML] Serotonin 2B receptor antagonism prevents heritable pulmonary arterial hypertension

…, AK Schroer, P Chen, LM Ryzhova, S Gladson, S Shay… - PloS one, 2016 - journals.plos.org
… For measurements of activated TGF-β1, a 1:1 dilution of media to serum-free Dulbecco’s
modification of Eagle’s medium (DMEM, Corning CellGro) was prepared, and for …

Myeloid cell derived IL1β contributes to pulmonary hypertension in HFpEF

…, T Blackwell, DK Gupta, MH Talati, S Gladson… - Circulation …, 2023 - Am Heart Assoc
BACKGROUND: Pulmonary hypertension (PH) in heart failure with preserved ejection
fraction (HFpEF) is a common and highly morbid syndrome, but mechanisms driving PH-HFpEF …