[HTML][HTML] Diagnostics for SARS-CoV-2 infections
… Such tests determine an immune response against the viral spike (S) protein and may be
helpful to assess … The intent is to facilitate the containment of the virus’s global spread 12,15 . …
helpful to assess … The intent is to facilitate the containment of the virus’s global spread 12,15 . …
[HTML][HTML] Nanocarriers for ocular drug delivery: Current status and translational opportunity
S Gorantla, VK Rapalli, T Waghule, PP Singh… - RSC …, 2020 - pubs.rsc.org
Ocular diseases have a significant effect on vision and quality of life. Drug delivery to ocular
tissues is a challenge to formulation scientists. The major barriers to delivering drugs to the …
tissues is a challenge to formulation scientists. The major barriers to delivering drugs to the …
Biodegradable microneedles fabricated with carbohydrates and proteins: Revolutionary approach for transdermal drug delivery
… It was found that polyvinyl pyrrolidone (PVP) coating dissolved within 30 s in phosphate
buffer solution. They reported that PVP K15 dissolved even faster compared to PVP K30 [47]. …
buffer solution. They reported that PVP K15 dissolved even faster compared to PVP K30 [47]. …
Transformation-mediated ductility in CuZr-based bulk metallic glasses
Bulk metallic glasses (BMGs) generally fail in a brittle manner under uniaxial, quasistatic
loading at room temperature 1 . The lack of plastic strain is a consequence of shear softening 2 …
loading at room temperature 1 . The lack of plastic strain is a consequence of shear softening 2 …
Mechanism of alcohol-induced oxidative stress and neuronal injury
J Haorah, SH Ramirez, N Floreani, S Gorantla… - Free Radical Biology …, 2008 - Elsevier
… A 20 μl of 90 mM NAD was added to prewarmed cuvettes, and changes in optical density
were read at 340 nm using the time-drive kinetics for 10 min at 30-s intervals. ADH activity was …
were read at 340 nm using the time-drive kinetics for 10 min at 30-s intervals. ADH activity was …
Therapeutic immunization protects dopaminergic neurons in a mouse model of Parkinson's disease
…, V Jackson-Lewis, S Gorantla… - Proceedings of the …, 2004 - National Acad Sciences
Degeneration of the nigrostriatal dopaminergic pathway, the hallmark of Parkinson's disease,
can be recapitulated in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-intoxicated …
can be recapitulated in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-intoxicated …
[HTML][HTML] Sequential LASER ART and CRISPR treatments eliminate HIV-1 in a subset of infected humanized mice
…, JE McMillan, AN Bade, S Gorantla… - Nature …, 2019 - nature.com
… To affirm the model’s relevance for studies of HIV-1 elimination, we undertook a detailed
evaluation of each of the human cell-virus model components (Fig. 1). First, after irradiation of …
evaluation of each of the human cell-virus model components (Fig. 1). First, after irradiation of …
Alzheimer's disease brain-derived extracellular vesicles spread tau pathology in interneurons
…, J Hu, Y Wang, S Hersh, M Ericsson, S Gorantla… - Brain, 2021 - academic.oup.com
… Alzheimer’s disease extracellular vesicles were more … ’s disease and control extracellular
vesicles in vitro. Strikingly, the inoculation of Alzheimer’s disease or prodromal Alzheimer’s …
vesicles in vitro. Strikingly, the inoculation of Alzheimer’s disease or prodromal Alzheimer’s …
van der Waals epitaxial growth of graphene on sapphire by chemical vapor deposition without a metal catalyst
… With these techniques, the Raman D-peak significantly decreased, but the carrier
mobility did not improve much (531 cm 2 /V·s in ref 23 and 100–600 cm 2 /V·s in ref 24). High-…
mobility did not improve much (531 cm 2 /V·s in ref 23 and 100–600 cm 2 /V·s in ref 24). High-…
Induction of oxidative and nitrosative damage leads to cerebrovascular inflammation in an animal model of mild traumatic brain injury induced by primary blast
…, F Wang, M Skotak, J Jones, S Gorantla… - Free Radical Biology …, 2013 - Elsevier
We investigate the hypothesis that oxidative damage of the cerebral vascular barrier interface
(the blood–brain barrier, BBB) causes the development of mild traumatic brain injury (TBI) …
(the blood–brain barrier, BBB) causes the development of mild traumatic brain injury (TBI) …