User profiles for S. Grinstein

Sebastian Grinstein

- Verified email at ifae.es - Cited by 301973

Sergio Grinstein

- Verified email at sickkids.ca - Cited by 77227

Sensors and regulators of intracellular pH

JR Casey, S Grinstein, J Orlowski - Nature reviews Molecular cell …, 2010 - nature.com
Protons dictate the charge and structure of macromolecules and are used as energy currency
by eukaryotic cells. The unique function of individual organelles therefore depends on the …

The cell biology of phagocytosis

…, V Jaumouillé, S Grinstein - Annual Review of …, 2012 - annualreviews.org
Engulfment and destruction of invading microorganisms by phagocytosis are critical
components of the innate immune response. In addition, phagocytosis is also required for the …

Antimicrobial mechanisms of phagocytes and bacterial evasion strategies

RS Flannagan, G Cosío, S Grinstein - Nature Reviews Microbiology, 2009 - nature.com
Professional phagocytes have a vast and sophisticated arsenal of microbicidal features.
They are capable of ingesting and destroying invading organisms, and can present microbial …

[HTML][HTML] Production and integration of the ATLAS Insertable B-Layer

…, H Gray, I Gregor, P Grenier, S Grinstein… - Journal of …, 2018 - iopscience.iop.org
The ATLAS [1] general purpose detector is used for the study of proton-proton (pp) and heavy-ion
collisions at the CERN Large Hadron Collider (LHC)[2]. It successfully collected data at …

Robust single-particle tracking in live-cell time-lapse sequences

…, D Loerke, M Mettlen, H Kuwata, S Grinstein… - Nature …, 2008 - nature.com
… I merging with a middle point of track segment J; s IJ , cost for the start of track segment J …
We captured image streams at 10 Hz for 10 s using an electron-multiplying charge-coupled …

Phagocytosis and innate immunity

S Greenberg, S Grinstein - Current opinion in immunology, 2002 - Elsevier
… The identity of specific phosphatase(s) that dephosphorylate phospho-cofilin in vivo is
unknown. The major kinases that phosphorylate cofilin are LIM kinases 1 and 2 45., 46., but other …

The Unc93b1 mutation 3d disrupts exogenous antigen presentation and signaling via Toll-like receptors 3, 7 and 9

…, T Wiltshire, BE Steinberg, S Grinstein… - Nature …, 2006 - nature.com
Here we have identified 'triple D' (3d), a recessive N-ethyl-N-nitrosourea-induced mutation
and phenotype in which no signaling occurs via the intracellular Toll-like receptors 3, 7 and 9 (…

Run II jet physics: proceedings of the run II QCD and weak boson physics workshop

…, SD Ellis, VD Elvira, K Frame, S Grinstein… - arXiv preprint hep-ex …, 2000 - arxiv.org
… radius R around the central parton(s). However, if the partons … s/2 applies only for collinear
particles and massless jets. In the case of massive jets the boundary for ET is larger than √s

Membrane phosphatidylserine regulates surface charge and protein localization

…, GE Gilbert, J Shi, J Silvius, A Kapus, S Grinstein - Science, 2008 - science.org
Electrostatic interactions with negatively charged membranes contribute to the subcellular
targeting of proteins with polybasic clusters or cationic domains. Although the anionic …

The distribution and function of phosphatidylserine in cellular membranes

PA Leventis, S Grinstein - Annual review of biophysics, 2010 - annualreviews.org
… Regardless of the specific mechanism(s) involved, the exposure of PS on the cytosolic
aspect of secretory membranes is likely to participate in their generation and trafficking, which …