User profiles for S. Hawinkel

Stijn Hawinkel

Postdoctoral researcher, Ghent University/VIB, Belgium
Verified email at ugent.be
Cited by 266

A broken promise: microbiome differential abundance methods do not control the false discovery rate

S Hawinkel, F Mattiello, L Bijnens… - Briefings in …, 2019 - academic.oup.com
… with r i j P e a r s o n the observed Pearson residual and ϕ j , s i and ρ j the estimated
dispersion, … Stijn Hawinkel is a PhD student in biostatistics in the BioStat group, Department of …

[HTML][HTML] Predicting yield of individual field-grown rapeseed plants from rosette-stage leaf gene expression

…, M Van de Voorde, S Hawinkel… - PLoS computational …, 2023 - journals.plos.org
… This is mostly due to differences in the way Moran’s I values and their significance were
calculated in the present study versus Cruz et al. [28] (use of a queen contiguity-based spatial …

[HTML][HTML] Sequence count data are poorly fit by the negative binomial distribution

S Hawinkel, JCW Rayner, L Bijnens, O Thas - PloS one, 2020 - journals.plos.org
… if an intercept is to be included in the model. We consider NB regression models of the form
where ϕ is the overdispersion parameter and (1) in which β 0 is a given constant, which is

Out-of-Sample R2: Estimation and Inference

S Hawinkel, W Waegeman, S Maere - The American Statistician, 2024 - Taylor & Francis
… Out-of-sample prediction is the acid test of predictive models, yet an independent test dataset
is often not available for assessment of … Our method is available in the R-package oosse. …

[HTML][HTML] Spatial regression models for field trials: a comparative study and new ideas

S Hawinkel, S De Meyer, S Maere - Frontiers in plant science, 2022 - frontiersin.org
… included in model components other than the regressors since â i is calculated after
omitting all spatial terms, ie, only β ^ is used for making predictions. The value of the Moran's I …

[HTML][HTML] A unified framework for unconstrained and constrained ordination of microbiome read count data

S Hawinkel, FM Kerckhof, L Bijnens, O Thas - PLoS One, 2019 - journals.plos.org
is not well adapted to skewed data, and its mean-variance assumption is too rigid to account
for the overdispersion which is … , we add the p taxon scores s j1 versus s j2 as arrows on the …

Model-based joint visualization of multiple compositional omics datasets

S Hawinkel, L Bijnens, KAL Cao… - NAR Genomics and …, 2020 - academic.oup.com
… The integration of multiple omics datasets measured on the same samples is a challenging
task: data come from heterogeneous … Our algorithm is available in the R-package combi. …

Predicting yield traits of individual field-grown Brassica napus plants from rosette-stage leaf gene expression

…, K Bird, H Sprenger, M Van de Voorde, S Hawinkel… - bioRxiv, 2022 - biorxiv.org
… Our results show that profiling individual plants under uncontrolled field conditions is a
valid strategy for identifying genes and processes influencing crop yield in the field. …

[PDF][PDF] Evaluation of normalization and analysis methods for microbiome data

S Hawinkel - MSc (Unpublished), Universiteit Gent, Belgium, 2015 - libstore.ugent.be
… DNA is a molecule that stores the genetic information of a cell, and its sequence is a
unique fingerprint of an organism. Reading off the sequence of a small part of a cell’s DNA is

Exploring anti-TGF-β therapies in cancer and fibrosis

LJAC Hawinkels, P Ten Dijke - Growth factors, 2011 - Taylor & Francis
… TGF-β will first bind to betaglycan and is then subsequently … , ALK5 is recruited,
betaglycan dissociates, and ALK-5 is … Systemic sclerosis is an autoimmune disease, which is