… S/N, will be lower for an underfilled back aperture. Therefore, a tradeoff has to be made
between increasing the S/N and minimizing artifacts by underfilling the objective back aperture. …

… Figure 6, central to the strategy for elimination of the malignant T cell population is the use
of agents that can induce apoptosis of these cells while simultaneously enhancing the host’s …

… (b) Simulated images of a diffusing isotropic emitter with D = 0.01 μm 2 /s and D = 1 μm 2 /s
that contain Poisson noise and pixelation. For both cases, a Brownian motion trajectory was …

… We also now recommend that researchers include in their Discussion section(s) an
honest assessment of how expectations and biases influenced the data analysis. Given this …

… 2, we can rationalize the increase in δ S 0 →S 2 on going from trans-stilbene to 4,4′-bis(…
the S 1 to S 2 transition dipole moment (M 12 ) from 3.1 to 7.2 D, (ii) an increase in the S 0 to S …

Biological structures span many orders of magnitude in size, but far-field visible light
microscopy suffers from limited resolution. A new method for fluorescence imaging has been …

… s Stephen Hess starts his twenty-fifth year as a senior fellow at Brookings, we are pleased
to publish two volumes of his essays about the institutions that have been the primary focus of …

… This simplifying theoretical description neglects the constraints on membrane domain areas
and surface-to-volume ratio (s/v), which are constant on the timescale of our experiment (up …

Many long non-coding RNAs (lncRNAs) affect gene expression 1 , but the mechanisms by
which they act are still largely unknown 2 . One of the best-studied lncRNAs is Xist, which is …

The current manuscript is an update of the original Practical Guide, published in June 2013[Heidbuchel
H, Verhamme P, Alings M, Antz M, Hacke W, Oldgren J, et al. European Heart …