User profiles for S. Holtze

Sara Holtz

- Verified email at msh.org - Cited by 1173

Stephen Holtz

- Verified email at hms.harvard.edu - Cited by 673

[HTML][HTML] Alternative animal models of aging research

S Holtze, E Gorshkova, S Braude… - Frontiers in Molecular …, 2021 - frontiersin.org
… Compared to their body size which lies between that of mice and rats, Fukomys species are
very long-lived: maximum lifespans of > 20 years have been reported for the Ansell’s mole-…

Neoteny, prolongation of youth: from naked mole rats to “naked apes”(humans)

VP Skulachev, S Holtze, MY Vyssokikh… - Physiological …, 2017 - journals.physiology.org
… These age-induced defects may cause death in a wild mouse, but their effects are likely
much less severe for the naked mole rat “queen” and her “husband(s)” living underground in the …

Surprisingly long survival of premature conclusions about naked mole‐rat biology

S Braude, S Holtze, S Begall, J Brenmoehl… - Biological …, 2021 - Wiley Online Library
… (IZW) (TB Hildebrandt & S. Holtze, personal observations) and also for several Fukomys
species studied by S. Begall and P. Dammann at the University of Duisburg-Essen and R. …

Robust induction of primordial germ cells of white rhinoceros on the brink of extinction

…, S Holtze, G Lazzari, C Galli, J Stejskal, S Diecke… - Science …, 2022 - science.org
In vitro gametogenesis, the process of generating gametes from pluripotent cells in culture,
is a powerful tool for improving our understanding of germ cell development and an …

Mild depolarization of the inner mitochondrial membrane is a crucial component of an anti-aging program

MY Vyssokikh, S Holtze, OA Averina… - Proceedings of the …, 2020 - National Acad Sciences
… In 1997, one of the authors of this paper (VPS) and his coworkers S. Korshunov and A.
Starkov reported that a rather small decrease in the mitochondrial electric potential results in the …

Fly Cell Atlas: A single-nucleus transcriptomic atlas of the adult fruit fly

…, S Gumbin, Y Guo, DE Harris, Y Heifetz, SL Holtz… - Science, 2022 - science.org
For more than 100 years, the fruit fly Drosophila melanogaster has been one of the most
studied model organisms. Here, we present a single-cell atlas of the adult fly, Tabula …

Rewinding the process of mammalian extinction

…, K Hayashi, R Hermes, S Holtze, S Johnson… - Zoo …, 2016 - Wiley Online Library
With only three living individuals left on this planet, the northern white rhinoceros (Ceratotherium
simum cottoni) could be considered doomed for extinction. It might still be possible, …

[HTML][HTML] Embryos and embryonic stem cells from the white rhinoceros

…, R Hermes, S Colleoni, S Diecke, S Holtze… - Nature …, 2018 - nature.com
… credit to the original author(s) and the source, provide a … ’s Creative Commons license,
unless indicated otherwise in a credit line to the material. If material is not included in the article’s

Somatosensory activation of two fingers can be discriminated with ultrahigh-density diffuse optical tomography

C Habermehl, S Holtze, J Steinbrink, SP Koch, H Obrig… - Neuroimage, 2012 - Elsevier
… of vibrotactile stimulation of the d1 (blue background) followed by 20 s resting. For … t = − 10
s to t = − 1 s and a time range for stimulus response from t = 13 s to t = 20 s (last 7 s of stimulus)…

The microenvironment of naked mole‐rat burrows in East Africa

S Holtze, S Braude, A Lemma, R Koch… - African Journal of …, 2018 - Wiley Online Library
… Shams, Nevo, & Avivi (2005b) have hypothesized that one anticancer pathway in blind
mole-rats (S. ehrenbergi) results from highly regulated VEGF. VEGF is typically up-regulated in …