… putative Eed translation start sites to confirm Eed’s role in mono-, di- and trimethylation of …
in transient lines than in stable lines, even though only Eedhypo’s ability to mediate H3K27 …

Polycomb repressive complexes 1 and 2 (PRC1 and 2) play a critical role in the epigenetic
regulation of transcription during cellular differentiation, stem cell pluripotency and neoplastic …

… , followed twice with ice-cold CSK for 30 s each time. All CSK buffers were supplemented with
… Embryos were then mounted on a glass coverslip coated with 1× Denhardt’s solution in a …

Dioxygenases of the TET (Ten-Eleven Translocation) family produce oxidized methylcytosines,
intermediates in DNA demethylation, as well as new epigenetic marks. Here we show …

We demonstrate that dissociated human pluripotent stem cells (PSCs) are intrinsically
programmed to form lumens. PSCs form two-cell cysts with a shared apical domain within 20 hr of …

Dysregulated translation is a common feature of cancer. Uncovering its governing factors and
underlying mechanism are important for cancer therapy. Here, we report that enhancer of …

… Cultured or cytopspun cells were permeabilized by sequential 30 s incubations in ice-cold …
We also acknowledge S. Mlynarczyk-Evnas for technical advice on FISH. SK is a recipient …

Much work over the last three decades has established that chemical modifications of DNA
and histones are intimately linked with various facets of DNA metabolism, most notably …

… 30 s, ice-cold CSK buffer containing 0.4% Triton X-100 (Fisher Scientific, #EP151) for 30 s,
followed twice with ice-cold CSK for 30 s … All three amplicons span intron(s), thus permitting …

The Polycomb group (PcG) proteins are thought to silence gene expression by modifying
chromatin. The Polycomb repressive complex 2 (PRC2) plays an essential role in mammalian X…