User profiles for S. Le Crom

Stéphane Le Crom

Professor of Genomics, Sorbonne Université
Verified email at sorbonne-universite.fr
Cited by 6527

Evolution and cell biology of dopamine receptors in vertebrates

S Callier, M Snapyan, S Le Crom, D Prou… - Biology of the …, 2003 - Wiley Online Library
Dopamine, one of main modulatory neurotransmitters of the nervous system acts on target
cells through two classes of G protein‐coupled receptors, D 1 and D 2 . The two dopamine …

A comprehensive evaluation of normalization methods for Illumina high-throughput RNA sequencing data analysis

…, C Le Gall, B Schaëffer, S Le Crom… - Briefings in …, 2013 - academic.oup.com
During the last 3 years, a number of approaches for the normalization of RNA sequencing
data have emerged in the literature, differing both in the type of bias adjustment and in the …

[HTML][HTML] Comparative genome sequence analysis underscores mycoparasitism as the ancestral life style of Trichoderma

…, L Karaffa, I Kosti, S Le Crom, E Lindquist, S Lucas… - Genome biology, 2011 - Springer
Background Mycoparasitism, a lifestyle where one fungus is parasitic on another fungus,
has special relevance when the prey is a plant pathogen, providing a strategy for biological …

Dopamine D1 and adenosine A1 receptors form functionally interacting heteromeric complexes

…, J Hillion, M Torvinen, S Le Crom… - Proceedings of the …, 2000 - National Acad Sciences
The possible molecular basis for the previously described antagonistic interactions between
adenosine A 1 receptors (A 1 R) and dopamine D 1 receptors (D 1 R) in the brain have …

[HTML][HTML] Yeast mitochondrial biogenesis: a role for the PUF RNA-binding protein Puf3p in mRNA localization

…, T Delaveau, L Jourdren, S Le Crom, S Lemoine… - PloS one, 2008 - journals.plos.org
The asymmetric localization of mRNA plays an important role in coordinating posttranscriptional
events in eukaryotic cells. We investigated the peripheral mitochondrial localization of …

Tracking the roots of cellulase hyperproduction by the fungus Trichoderma reesei using massively parallel DNA sequencing

S Le Crom, W Schackwitz… - Proceedings of the …, 2009 - National Acad Sciences
Trichoderma reesei (teleomorph Hypocrea jecorina) is the main industrial source of cellulases
and hemicellulases harnessed for the hydrolysis of biomass to simple sugars, which can …

[HTML][HTML] The CRE1 carbon catabolite repressor of the fungus Trichoderma reesei: a master regulator of carbon assimilation

…, L Hartl, L Karaffa, IS Druzhinina, B Seiboth, S Le Crom… - BMC genomics, 2011 - Springer
Background The identification and characterization of the transcriptional regulatory networks
governing the physiology and adaptation of microbial cells is a key step in understanding …

Eoulsan: a cloud computing-based framework facilitating high throughput sequencing analyses

L Jourdren, M Bernard, MA Dillies, S Le Crom - Bioinformatics, 2012 - academic.oup.com
We developed a modular and scalable framework called Eoulsan, based on the Hadoop
implementation of the MapReduce algorithm dedicated to high-throughput sequencing data …

[HTML][HTML] Translation in astrocyte distal processes sets molecular heterogeneity at the gliovascular interface

…, C Blugeon, S Perrin, J Pouch, B Ducos, S Le Crom… - Cell discovery, 2017 - nature.com
Astrocytes send out long processes that are terminated by endfeet at the vascular surface
and regulate vascular functions as well as homeostasis at the vascular interface. To date, the …

Differential regulation of the cellulase transcription factors XYR1, ACE2, and ACE1 in Trichoderma reesei strains producing high and low levels of cellulase

T Portnoy, A Margeot, V Seidl-Seiboth, S Le Crom… - Eukaryotic …, 2011 - Am Soc Microbiol
… Margeot and S. Le Crom, unpublished data). We also sequenced the loci of xyr1, ace1, and
ace2 in CL847 and found that neither their promoter regions nor their open reading frames (…