User profiles for S. Lelievre
Sophie LelievrePurdue University Verified email at purdue.edu Cited by 5549 |
Tissue structure, nuclear organization, and gene expression in normal and malignant breast
MJ Bissell, VM Weaver, SA Lelièvre, F Wang… - Cancer research, 1999 - AACR
… Given this behavioral range and the possibility that nuclear architecture itself may impart
important behavioral cues (58), we investigated whether these progressive stages of S 1 cell …
important behavioral cues (58), we investigated whether these progressive stages of S 1 cell …
ErbB2, but not ErbB1, reinitiates proliferation and induces luminal repopulation in epithelial acini
SK Muthuswamy, D Li, S Lelievre, MJ Bissell… - Nature cell …, 2001 - nature.com
Both ErbB1 and ErbB2 are overexpressed or amplified in breast tumours. To examine the
effects of activating ErbB receptors in a context that mimics polarized epithelial cells in vivo, we …
effects of activating ErbB receptors in a context that mimics polarized epithelial cells in vivo, we …
[PDF][PDF] β4 integrin-dependent formation of polarized three-dimensional architecture confers resistance to apoptosis in normal and malignant mammary epithelium
… the nonmalignant S-1 cells at passages 50–70 (“normal”; S-1) … Control S-1 structures in
rBM, S-1 in collagen I gels, and S-1 … B: BrdU labeling indices for S-1 cells incorporated into 3D …
rBM, S-1 in collagen I gels, and S-1 … B: BrdU labeling indices for S-1 cells incorporated into 3D …
Architecture in 3D cell culture: An essential feature for in vitro toxicology
SA Lelièvre, T Kwok, S Chittiboyina - Toxicology in vitro, 2017 - Elsevier
Three-dimensional cell culture has the potential to revolutionize toxicology studies by allowing
human-based reproduction of essential elements of organs. Beyond the study of toxicants …
human-based reproduction of essential elements of organs. Beyond the study of toxicants …
Tissue phenotype depends on reciprocal interactions between the extracellular matrix and the structural organization of the nucleus
SA Lelièvre, VM Weaver… - Proceedings of the …, 1998 - National Acad Sciences
… The antibody-directed disruption of NuMA foci in the acini induced changes in the distribution
pattern of acetylated histone H4, the activation of metalloprotease(s), and the loss of BM …
pattern of acetylated histone H4, the activation of metalloprotease(s), and the loss of BM …
Redefining the impact of nutrition on breast cancer incidence: is epigenetics involved?
D Teegarden, I Romieu, SA Lelievre - Nutrition research reviews, 2012 - cambridge.org
… The 20-year predictions for large increases in breast cancer incidence and mortality in LMI
regions(1) substantiate the urgency of the WHO’s call for actions to support primary cancer …
regions(1) substantiate the urgency of the WHO’s call for actions to support primary cancer …
High resolution protein localization using soft X‐ray microscopy
…, D Hamamoto, A Nair, SA Lelievre… - Journal of …, 2001 - Wiley Online Library
… Freezing rates of 3000 C s −1 are not sufficient to achieve vitreous ice and well-frozen cells.
Examination of the same cells using electron microscopy might reveal ice crystal damage …
Examination of the same cells using electron microscopy might reveal ice crystal damage …
Segmentation of nuclei and cells using membrane related protein markers
…, R Malladi, SA Lelievre… - journal of …, 2001 - Wiley Online Library
… Immunostaining was performed using a protocol already described (Lelièvre et al., 1998).
Mouse IgG1 anti-laminB antibody was purchased from … Bissell for providing the S 1−50 cells. …
Mouse IgG1 anti-laminB antibody was purchased from … Bissell for providing the S 1−50 cells. …
Suramin is an inhibitor of DNA topoisomerase II in vitro and in Chinese hamster fibrosarcoma cells.
K Bojanowski, S Lelievre, J Markovits… - Proceedings of the …, 1992 - National Acad Sciences
The antitrypanosomal and antifiliarial drug suramin is currently under investigation for treatment
of advanced malignancies including prostatic cancer, adrenocortical cancer, and some …
of advanced malignancies including prostatic cancer, adrenocortical cancer, and some …
Diet alters entero-mammary signaling to regulate the breast microbiome and tumorigenesis
…, MU Ramirez, GL Kucera, EA Levine, SA Lelievre… - Cancer research, 2021 - AACR
This study demonstrates that diet shifts the microbiome in the gut and the breast tumor
microenvironment to affect tumorigenesis, and oral dietary interventions can modulate the tumor …
microenvironment to affect tumorigenesis, and oral dietary interventions can modulate the tumor …