We have used the interaction trap, a yeast two-hybrid system, to identify proteins Interacting
with hairy, a basic-helix-loop-helix (bHLH) protein that represses transcription during …

The Groucho (Gro)/TLE/Grg family of corepressors operates in many signaling pathways (including
Notch and Wnt). Gro/TLE proteins recognize a wide range of transcriptional …

Male reproductive glands secrete signals into seminal fluid to facilitate reproductive success.
In Drosophila melanogaster, these signals are generated by a variety of seminal peptides, …

Exosomes are secreted nanovesicles with potent signalling activity that are initially formed
as intraluminal vesicles (ILVs) in late Rab7‐positive multivesicular endosomes, and also in …

The evolutionarily conserved Ras/mitogen-activated protein kinase (MAPK) cascade is an
integral part of the processes of cell division, differentiation, movement and death. Signals …

Patterning of the non-segmental termini of the Drosophila embryo depends on signalling via
the Torso receptor tyrosine kinase (RTK). Activation of Torso at the poles of the embryo …

Seminal fluid plays an essential role in promoting male reproductive success and modulating
female physiology and behavior. In the fruit fly, Drosophila melanogaster, Sex Peptide (SP) …

The Drosophila pair-rule gene, hairy (h), encodes a nuclear basic helix-loop-helix (bHLH)
protein that regulates embryonic segmentation and adult bristle patterning. In both cases, the …

Secretory cells in glands and the nervous system frequently package and store proteins
destined for regulated secretion in dense-core granules (DCGs), which disperse when released …

The Groucho (Gro)/transducin‐like enhancer of split family of transcriptional corepressors
are implicated in many signalling pathways that are important in development and disease, …