User profiles for S. Mortlock

Sally Mortlock

Institute for Molecular Bioscience, University of Queensland
Verified email at uq.edu.au
Cited by 811

Insights from Mendelian randomization and genetic correlation analyses into the relationship between endometriosis and its comorbidities

…, GW Montgomery, S Mortlock - Human Reproduction …, 2023 - academic.oup.com
… Endometriosis is a complex disease, which means both genetic and environmental factors
contribute to an individual’s disease liability. A recent genome-wide association study (GWAS…

The genetic basis of endometriosis and comorbidity with other pain and inflammatory conditions

N Rahmioglu, S Mortlock, M Ghiasi, PL Møller… - Nature …, 2023 - nature.com
Endometriosis is a common condition associated with debilitating pelvic pain and infertility.
A genome-wide association study meta-analysis, including 60,674 cases and 701,926 …

Should genetics now be considered the pre-eminent etiologic factor in endometriosis?

GW Montgomery, S Mortlock, LC Giudice - Journal of minimally invasive …, 2020 - Elsevier
… If genetic factors are to explain the etiology of endometriosis, the evidence should identify
the origin(s) of cells responsible for initiation of lesions, differences in the types and locations …

[HTML][HTML] Genetic regulation of physiological reproductive lifespan and female fertility

IM McGrath, S Mortlock, GW Montgomery - International Journal of …, 2021 - mdpi.com
… additive effects of 100 s or 1000 s of individual variants across … effects because the same
variant(s) are associated with many … , the same causal variant(s) effect hormonal concentrations …

Characterisation of the species responsible for yellowing in melt degraded aromatic polyesters—I: Yellowing of poly (ethylene terephthalate)

…, R Wiles, NS Allen, WA McDonald, SV Mortlock - … degradation and stability, 1996 - Elsevier
Changes in the luminescence, infra-red and visible spectra of poly(ethylene terephthalate) (PET)
when degraded at melt temperatures in air and nitrogen have been examined. Main …

[HTML][HTML] Genome-wide association and epidemiological analyses reveal common genetic origins between uterine leiomyomata and endometriosis

…, DR Velez-Edwards, TL Edwards, S Mortlock… - Nature …, 2019 - nature.com
Uterine leiomyomata (UL) are the most common neoplasms of the female reproductive tract
and primary cause for hysterectomy, leading to considerable morbidity and high economic …

[PDF][PDF] A multi-level investigation of the genetic relationship between endometriosis and ovarian cancer histotypes

S Mortlock, RI Corona, PF Kho, P Pharoah, JH Seo… - Cell Reports …, 2022 - cell.com
Endometriosis is associated with increased risk of epithelial ovarian cancers (EOCs). Using
data from large endometriosis and EOC genome-wide association meta-analyses, we …

[HTML][HTML] Genotype-free demultiplexing of pooled single-cell RNA-seq

…, BD McKinnon, S Mortlock, A Senabouth, S Andersen… - Genome biology, 2019 - Springer
… , and let pseudo A R be the pseudo allele count for both Alternative and Reference alleles,
and pseudo A be the pseudo allele count for Alternative alleles, we calculated P(A v |S n ), …

[HTML][HTML] Genetic regulation of disease risk and endometrial gene expression highlights potential target genes for endometriosis and polycystic ovarian syndrome

JN Fung, S Mortlock, JE Girling… - Scientific reports, 2018 - nature.com
Gene expression varies markedly across the menstrual cycle and expression levels for many
genes are under genetic control. We analyzed gene expression and mapped expression …

Tissue specific regulation of transcription in endometrium and association with disease

S Mortlock, RI Kendarsari, JN Fung… - Human …, 2020 - academic.oup.com
… Total RNA was isolated from endometrial tissue using the Allprep DNA/RNA Mini Kit (Qiagen,
CA) as per the manufacturer’s instructions. RNA quality was checked using the …