User profiles for S. Paabo

Svante Paabo

Verified email at eva.mpg.de
Cited by 136128

[PDF][PDF] Ancient DNA and the polymerase chain reaction: the emerging field of molecular archaeology (Minireview)

S Pääbo, RG Higuchi, AC Wilson - The Journal of biological chemistry, 1989 - pure.mpg.de
… the close relationship of elephant and mammoth albumins (12); it also placed the extinct
Tasmanian wolf within the genealogical tree for extant carnivorous marsupials (12) and Steller’s

Evolution of primate gene expression

…, W Enard, M Lachmann, S Pääbo - Nature Reviews …, 2006 - nature.com
It has been suggested that evolutionary changes in gene expression account for most
phenotypic differences between species, in particular between humans and apes. What general …

The Neandertal genome and ancient DNA authenticity

…, M Siebauer, M Lachmann, S Pääbo - The EMBO …, 2009 - embopress.org
Recent advances in high‐thoughput DNA sequencing have made genome‐scale analyses
of genomes of extinct organisms possible. With these new opportunities come new difficulties …

Dynamics of mitochondrial DNA evolution in animals: amplification and sequencing with conserved primers.

…, A Meyer, SV Edwards, S Pääbo… - Proceedings of the …, 1989 - National Acad Sciences
… Sources of DNA include dried skins (S) up to 80 years old, tissues preserved in alcohol (A), …
The rate of replacement is about S times lower in the lineage leading to fish (F) than on …

The complete genome sequence of a Neanderthal from the Altai Mountains

…, B Viola, M Slatkin, D Reich, J Kelso, S Pääbo - Nature, 2014 - nature.com
We present a high-quality genome sequence of a Neanderthal woman from Siberia. We
show that her parents were related at the level of half-siblings and that mating among close …

Mitochondrial genome variation and the origin of modern humans

M Ingman, H Kaessmann, S Pääbo, U Gyllensten - Nature, 2000 - nature.com
The analysis of mitochondrial DNA (mtDNA) has been a potent tool in our understanding of
human evolution, owing to characteristics such as high copy number, apparent lack of …

The genomic landscape of Neanderthal ancestry in present-day humans

…, S Mallick, M Dannemann, K Prüfer, J Kelso, S Pääbo… - Nature, 2014 - nature.com
… To assess significance, we estimated Spearman’s correlation ρ and standard errors on ρ
using a block jackknife 37 with 10-Mb blocks (Supplementary Information section 8). …

The evolution of gene expression levels in mammalian organs

…, F Grützner, S Bergmann, R Nielsen, S Pääbo… - Nature, 2011 - nature.com
… b, Spearman’s correlations between humans and the other species. Coloured envelopes
show ranges of values obtained in 100 bootstrap replicates. c, Expression evolution rates on …

Intra-and interspecific variation in primate gene expression patterns

…, A Varki, R Ravid, GM Doxiadis, RE Bontrop, S Paabo - Science, 2002 - science.org
Although humans and their closest evolutionary relatives, the chimpanzees, are 98.7%
identical in their genomic DNA sequences, they differ in many morphological, behavioral, and …

Ancient DNA: extraction, characterization, molecular cloning, and enzymatic amplification.

S Pääbo - Proceedings of the National Academy of …, 1989 - National Acad Sciences
… DNA was extracted by a modification of the Blin and Stafford procedure (15) that has been
described by Paabo et al. (16). After ethanol precipitation, a brown contaminant, probably …