User profiles for S. Sayols

sergi sayols

Institute of Molecular Biology Mainz
Verified email at imb-mainz.de
Cited by 7692

[PDF][PDF] A landscape of pharmacogenomic interactions in cancer

…, L Richardson, J Wang, T Zhang, S Moran, S Sayols… - Cell, 2016 - cell.com
Systematic studies of cancer genomes have provided unprecedented insights into the
molecular nature of cancer. Using this information to guide the development and application of …

Distinct DNA methylomes of newborns and centenarians

…, FJ Carmona, AA Puca, S Sayols… - Proceedings of the …, 2012 - National Acad Sciences
… P < 0.01 in the Fisher’s exact t test. The mean methylation level is calculated by the number
of total methylated reads divided by the numbers of total reads covering CpG sites located in …

Epigenetic profiling to classify cancer of unknown primary: a multicentre, retrospective analysis

S Moran, A Martínez-Cardús, S Sayols… - The Lancet …, 2016 - thelancet.com
… appearance under light microscopy, as well as immunohistochemical findings, including
cytokeratin 7 (CK7), cytokeratin 20 (CK20), vimentin, epithelial membrane antigens, and S-100 …

DNA methylation contributes to natural human variation

…, S Moran, I Hernando-Herraez, S Sayols… - Genome …, 2013 - genome.cshlp.org
DNA methylation patterns are important for establishing cell, tissue, and organism phenotypes,
but little is known about their contribution to natural human variation. To determine their …

[PDF][PDF] DNA methylation‐based prognosis and epidrivers in hepatocellular carcinoma

A Villanueva, A Portela, S Sayols, C Battiston… - …, 2015 - Wiley Online Library
… Kaplan-Meier’s plots and Cox’s … ’s model aimed to identify independent predictors of survival
and recurrence. Missing values were less than 10% for each variable included in the Cox’s

[PDF][PDF] A prognostic DNA methylation signature for stage I non-small-cell lung cancer

…, G Chen, FJ Carmona, S Sayols, S Moran… - Journal of clinical …, 2013 - iris.unito.it
… , the following author(s) and/or an author’s immediate family member(s) indicated a financial
or … categories, or for more information about ASCO’s conflict of interest policy, please refer to …

DNA methylation map of human atherosclerosis

…, H Heyn, FJ Carmona, N Varol, S Sayols… - Circulation …, 2014 - Am Heart Assoc
Background— Epigenetic alterations may contribute to the development of atherosclerosis.
In particular, DNA methylation, a reversible and highly regulated DNA modification, could …

Head-to-head antisense transcription and R-loop formation promotes transcriptional activation

…, A Portela, C Moutinho, S Sayols… - Proceedings of the …, 2015 - National Acad Sciences
The mechanisms used by antisense transcripts to regulate their corresponding sense mRNAs
are not fully understood. Herein, we have addressed this issue for the vimentin (VIM) gene…

[HTML][HTML] Epigenomic analysis detects aberrant super-enhancer DNA methylation in human cancer

…, S Sayols, A Gomez, S Moran, R Boque-Sastre, S Guil… - Genome biology, 2016 - Springer
… Significance was assessed by differential DNA methylation levels and the Student’s t-test
(p value), comparing normal and cancer samples and averaging over the analyzed CpG (≥3) …

[HTML][HTML] Gene amplification of the histone methyltransferase SETDB1 contributes to human lung tumorigenesis

…, L Simo-Riudalbas, S Sayols, C Moutinho, S Moran… - Oncogene, 2014 - nature.com
Disruption of the histone modification patterns is one of the most common features of human
tumors. However, few genetic alterations in the histone modifier genes have been …