User profiles for S. Sayols
sergi sayolsInstitute of Molecular Biology Mainz Verified email at imb-mainz.de Cited by 7692 |
[PDF][PDF] A landscape of pharmacogenomic interactions in cancer
Systematic studies of cancer genomes have provided unprecedented insights into the
molecular nature of cancer. Using this information to guide the development and application of …
molecular nature of cancer. Using this information to guide the development and application of …
Distinct DNA methylomes of newborns and centenarians
… P < 0.01 in the Fisher’s exact t test. The mean methylation level is calculated by the number
of total methylated reads divided by the numbers of total reads covering CpG sites located in …
of total methylated reads divided by the numbers of total reads covering CpG sites located in …
Epigenetic profiling to classify cancer of unknown primary: a multicentre, retrospective analysis
… appearance under light microscopy, as well as immunohistochemical findings, including
cytokeratin 7 (CK7), cytokeratin 20 (CK20), vimentin, epithelial membrane antigens, and S-100 …
cytokeratin 7 (CK7), cytokeratin 20 (CK20), vimentin, epithelial membrane antigens, and S-100 …
DNA methylation contributes to natural human variation
DNA methylation patterns are important for establishing cell, tissue, and organism phenotypes,
but little is known about their contribution to natural human variation. To determine their …
but little is known about their contribution to natural human variation. To determine their …
[PDF][PDF] DNA methylation‐based prognosis and epidrivers in hepatocellular carcinoma
A Villanueva, A Portela, S Sayols, C Battiston… - …, 2015 - Wiley Online Library
… Kaplan-Meier’s plots and Cox’s … ’s model aimed to identify independent predictors of survival
and recurrence. Missing values were less than 10% for each variable included in the Cox’s …
and recurrence. Missing values were less than 10% for each variable included in the Cox’s …
[PDF][PDF] A prognostic DNA methylation signature for stage I non-small-cell lung cancer
… , the following author(s) and/or an author’s immediate family member(s) indicated a financial
or … categories, or for more information about ASCO’s conflict of interest policy, please refer to …
or … categories, or for more information about ASCO’s conflict of interest policy, please refer to …
DNA methylation map of human atherosclerosis
Background— Epigenetic alterations may contribute to the development of atherosclerosis.
In particular, DNA methylation, a reversible and highly regulated DNA modification, could …
In particular, DNA methylation, a reversible and highly regulated DNA modification, could …
Head-to-head antisense transcription and R-loop formation promotes transcriptional activation
…, A Portela, C Moutinho, S Sayols… - Proceedings of the …, 2015 - National Acad Sciences
The mechanisms used by antisense transcripts to regulate their corresponding sense mRNAs
are not fully understood. Herein, we have addressed this issue for the vimentin (VIM) gene…
are not fully understood. Herein, we have addressed this issue for the vimentin (VIM) gene…
[HTML][HTML] Epigenomic analysis detects aberrant super-enhancer DNA methylation in human cancer
… Significance was assessed by differential DNA methylation levels and the Student’s t-test
(p value), comparing normal and cancer samples and averaging over the analyzed CpG (≥3) …
(p value), comparing normal and cancer samples and averaging over the analyzed CpG (≥3) …
[HTML][HTML] Gene amplification of the histone methyltransferase SETDB1 contributes to human lung tumorigenesis
Disruption of the histone modification patterns is one of the most common features of human
tumors. However, few genetic alterations in the histone modifier genes have been …
tumors. However, few genetic alterations in the histone modifier genes have been …