User profiles for S. Seizova

Simona Seizova

Postdoctoral Researcher, Walter and Eliza Hall Institute (WEHI) for Medical Research
Verified email at wehi.edu.au
Cited by 266

Toxoplasmosis: a pathway to neuropsychiatric disorders

S Tyebji, S Seizova, AJ Hannan, CJ Tonkin - … & Biobehavioral Reviews, 2019 - Elsevier
… Researchers have now identified numerous factors that could impact a person’s tendency
to … gut-brain cross-talk that affects a person’s mood, motivation, cognitive abilities as well as …

Toxoplasma protein export and effector function

S Seizova, A Ferrel, J Boothroyd, CJ Tonkin - Nature Microbiology, 2024 - nature.com
… Here they have a role in countering some of a rodent cell’s most potent defences, the
immunity-related guanosine triphosphatases (IRGs) and p65 guanylate-binding proteins 12,13,14,…

Type 1 conventional dendritic cell fate and function are controlled by DC-SCRIPT

…, HD Coughlan, M Ashayeripanah, S Seizova… - Science …, 2021 - science.org
… Human foreskin fibroblasts were grown to confluence in Dulbecco’s modified Eagle’s
medium (DMEM) supplemented with 1% (v/v) GlutaMAX (Invitrogen) and 10% (v/v) Cosmic Calf …

[PDF][PDF] Transcriptional modification of host cells harboring Toxoplasma gondii bradyzoites prevents IFN gamma-mediated cell death

S Seizova, U Ruparel, AL Garnham, SM Bader… - Cell host & …, 2022 - cell.com
… These findings highlight the functional importance of host manipulation in Toxoplasma’s
of protein export by secreting proteins from the parasite’s dense granule (DG; DG proteins an…

Aspartyl protease 5 matures dense granule proteins that reside at the host-parasite interface in Toxoplasma gondii

MJ Coffey, LF Dagley, S Seizova, EA Kapp, G Infusini… - MBio, 2018 - Am Soc Microbiol
Toxoplasma gondii infects approximately 30% of the world’s population, causing disease
primarily during pregnancy and in individuals with weakened immune systems. Toxoplasma …

[HTML][HTML] An apically located hybrid guanylate cyclase–ATPase is critical for the initiation of Ca2+ signaling and motility in Toxoplasma gondii

L Yang, AD Uboldi, S Seizova, ML Wilde… - Journal of Biological …, 2019 - ASBMB
Protozoan parasites of the phylum Apicomplexa actively move through tissue to initiate and
perpetuate infection. The regulation of parasite motility relies on cyclic nucleotide-dependent …

Impaired social behaviour and molecular mediators of associated neural circuits during chronic Toxoplasma gondii infection in female mice

S Tyebji, S Seizova, AL Garnham, AJ Hannan… - Brain, behavior, and …, 2019 - Elsevier
… Pearson’s correlations were calculated between brain regions … Statistical analysis was
performed using the Student’s t-test … Student’s t-test (AE) or two-way ANOVA with Sidak’s multiple …

[HTML][HTML] Mode of action studies confirm on-target engagement of lysyl-tRNA synthetase inhibitor and lead to new selection marker for Cryptosporidium

JC Hanna, V Corpas-Lopez, S Seizova… - Frontiers in Cellular …, 2023 - ncbi.nlm.nih.gov
Methods We used C. parvum lysyl-tRNA synthetase (CpKRS) and DDD01510706 as a
target-compound pair to develop both chemical and genetic tools for mode of action studies for …

Journalistic discourse of freedom: A study of journalists' understanding of freedom in the Czech Republic and Serbia

…, A Němcová Tejkalová, F Láb, S Seizova - Journalism, 2021 - journals.sagepub.com
… When we ran Spearman’s rank-order correlation inside each country’s sample among the
influences perception and both freedom to select a news story and freedom to emphasize the …

Identification and characterisation of splicing regulators in Toxoplasma gondii

VV Lee, S Seizova, PJ McMillan, E McHugh, CJ Tonkin… - BioRxiv, 2021 - biorxiv.org
… ), we retrieved and aligned homologues from S. pombe, Arabidopsis thaliana, T. gondii and
P. … This is similar to S. pombe in which only a single SRPK or CLK homologue has been …