… Ca–Zn s have a major role in TGI-related neuronal loss, as findings in CA1 pyramidal
neurons undergoing OGD or in a TGI animal model indicate that inhibition of AMPAR Ca–Zn s is …

… More speculatively, Zn 2+ dis-homeostasis might also contribute to some degenerative
conditions, including Alzheimer’s disease. Further elucidation of the pathological actions of Zn 2+ …

Mounting evidences support the idea that endogenous ‘biometals', such as copper, iron,
zinc and exogenous ones such as aluminum, can be involved as factors or cofactors in the …

The endogenous cannabinoids (endocannabinoids) are lipid molecules that may mediate
retrograde signaling at central synapses and other forms of short-range neuronal …

… the hemispheres resuspended in plating medium, which consisted of media stock (Eagle’s …
acidification associated with glutamate receptor activation (Sensi et al., 1993; Irwin et al., 1994…

… The rate of ion transport was calculated from each graph (summarizing an individual
experiment) by a linear fit of the change in the fluorescence (ΔF) over a period of 30 s following …

ContextObesity, in particular abdominal adiposity, is associated with increased cardiovascular
morbidity and mortality through mechanisms possibly linking the metabolic disorder to …

Apoptosis of mouse neocortical neurons induced by serum deprivation or by staurosporine
was associated with an early enhancement of delayed rectifier (I K ) current and loss of total …

We used the ratioable fluorescent dye mag-fura-5 to measure intracellular free Zn 2+ ([Zn 2+
] i ) in cultured neocortical neurons exposed to neurotoxic concentrations of Zn 2+ in concert …

Synaptically released Zn 2+ can enter and cause injury to postsynaptic neurons. Microfluorimetric
studies using the Zn 2+ -sensitive probe, Newport green, examined levels of [Zn 2+ ] i …