CD4’T cells play a key role in regulating immune system function. When these regulatory
processes go awry, organ-specific autoimmune diseases may develop. Here, Roland Liblau, …

… Sheetz, RG Painter, and SJ Singer, unpublished results), a powerful diagnostic test for
actin-like properties (22). The entire complex peripheral because it is rapidly released free of …

An understanding of electron-initiated processes in aqueous systems and the subsequent
radical chemistry these processes induce is significant in such diverse fields as waste …

Background Constitutive activation of KIT receptor tyrosine kinase is critical in the pathogenesis
of gastrointestinal stromal tumors. Imatinib mesylate, a selective tyrosine kinase inhibitor, …

A powerful way to discover key genes with causal roles in oncogenesis is to identify
genomic regions that undergo frequent alteration in human cancers. Here we present high-…

A fluid mosaic model is presented for the gross organization and structure of the proteins
and lipids of biological membranes. The model is consistent with the restrictions imposed by …

Purpose: Most gastrointestinal stromal tumors (GISTs) express constitutively activated mutant
isoforms of KIT or kinase platelet-derived growth factor receptor alpha (PDGFRA) that are …

Background Following the emergency use authorisation of the Pfizer–BioNTech mRNA
COVID-19 vaccine BNT162b2 (international non-proprietary name tozinameran) in Israel, the …

T HE ERYTHROCYTES of certain individuals possess the capacity to undergo reversible
changes in shape in responseto changes in the partial pressure of oxygen. When the oxygen …

We propose that membranes whose proteins and polar lipids are distributed asymmetrically
in the two halves of the membrane bilayer can act as bilayer couples, ie, the two halves can …