Significance: Here, we review certain recent advances in oxidative stress and tumor
metabolism, which are related to understanding the contributions of the microenvironment in …

Background: A systematic review of literature published between 1980 and 2007, on the
incidence of myasthenia gravis, was undertaken. Methods: All relevant papers found through …

Tuberculosis and malaria together result in an estimated 5 million deaths annually. The
spread of multidrug resistance in the most pathogenic causative agents, Mycobacterium …

We have recently proposed a new model of cancer metabolism to explain the role of aerobic
glycolysis and L-lactate production in fueling tumor growth and metastasis. In this model, …

… To begin to assess the induction of a senescence phenotype, we first examined the
expression of CDKI’s (cyclin-dependent kinase inhibitors) and cyclin D1 in all three autophagic …

… 10 7 to 10 4 s –1 for resonances broadened by the first-order quadrupolar interaction and
10 5 to 10 3 s –1 for CT line shapes subject to second-order quadrupolar broadening. (96) …

Here, we present new genetic and morphological evidence that human tumors consist of two
distinct metabolic compartments. First, re-analysis of genome-wide transcriptional profiling …

… Although the molecular mechanism(s) that link autophagy with senescence are still unclear,
we propose that systemic induction of autophagy and increased protein turnover could lead …

… Future studies on the role(s) played by estrogens in testicular function are likely to benefit
from the development of new ER subtype selective agonists and antagonists, the use of …

Background Malignant pleural mesothelioma (MPM) has a poor overall survival with few
treatment options. Whole genome sequencing (WGS) combined with the immune features of …