User profiles for S. Wongkuna

Supapit Wongkuna

Department of Molecular Biology, Umeå University
Verified email at umu.se
Cited by 181

[PDF][PDF] Autophagy controls mucus secretion from intestinal goblet cells by alleviating ER stress

…, N Asulin, S Turjeman, M Werbner, S Wongkuna… - Cell host & …, 2023 - cell.com
… Additionally, our observation that Nod2 is needed to facilitate mucus secretion when ER
stress is reduced provides a possible explanation for the high frequency of mutations in this …

Identification of Clostridioides difficile-inhibiting gut commensals using culturomics, phenotyping, and combinatorial community assembly

S Ghimire, C Roy, S Wongkuna, L Antony, A Maji… - Msystems, 2020 - Am Soc Microbiol
… the gut following antibiotic treatment is a clear demonstration of this phenomenon. Clostridioides
difficile is a Gram-positive spore-forming anaerobe that is the leading cause of antibiotic…

Gut microbial dynamics during conventionalization of germfree chicken

M Thomas, S Wongkuna, S Ghimire, R Kumar… - Msphere, 2019 - Am Soc Microbiol
A gnotobiotic Gallus gallus (chicken) model was developed to study the dynamics of intestinal
microflora from hatching to 18 days of age employing metagenomics. Intestinal samples …

[HTML][HTML] Frontiers in antibiotic alternatives for Clostridioides difficile infection

…, P Harnvoravongchai, S Wongkuna… - World Journal of …, 2021 - ncbi.nlm.nih.gov
… The next epidemic of CDI is not a matter of if but a matter of when. Therefore, being well-equipped
with a collection of alternative therapeutics is necessary and should be prioritized. …

Identification of a microbial sub-community from the feral chicken gut that reduces Salmonella colonization and improves gut health in a gnotobiotic chicken model

S Wongkuna, A Ambat, S Ghimire… - Microbiology …, 2024 - Am Soc Microbiol
… that inhibitory activity is lost in the cell-free supernatant indicating that inhibition is mediated
… Our results also showed that this inhibition is not serotype dependent and is applicable to …

[HTML][HTML] Temporal Variations in Patterns of Clostridioides difficile Strain Diversity and Antibiotic Resistance in Thailand

S Wongkuna, T Janvilisri, M Phanchana… - Antibiotics, 2021 - mdpi.com
… The pathogenesis of CDI is attributed to the production of two major toxins: toxins A and B.
Toxin A is an enterotoxin encoded by tcdA, and toxin B is a cytotoxin encoded by tcdB. Both …

A history of repeated antibiotic usage leads to microbiota-dependent mucus defects

KL Krigul, RH Feeney, S Wongkuna, O Aasmets… - bioRxiv, 2024 - biorxiv.org
… The copyright holder for this preprint is the author/funder, who has granted bioRxiv a
license to display the preprint in perpetuity. It is made available under a CC-BY-NC-ND 4.0 …

[HTML][HTML] Taxono-genomics description of Olsenella lakotia SW165 T sp. nov., a new anaerobic bacterium isolated from cecum of feral chicken

S Wongkuna, S Ghimire, T Janvilisri, K Doerner… - …, 2020 - ncbi.nlm.nih.gov
Background: The microbial community residing in the animal gastrointestinal tract play a
crucial role in host health. Because of the high complexity of gut microbes, many microbes …

[HTML][HTML] Positive Synergistic Effects of Quercetin and Rice Bran on Human Gut Microbiota Reduces Enterobacteriaceae Family Abundance and Elevates Propionate …

S Ghimire, S Wongkuna, R Sankaranarayanan… - Frontiers in …, 2021 - frontiersin.org
… When the combined effect of quercetin and rice bran were analyzed, we find that majority
of the microbial shift is due to the supplementation of rice bran (Figure 2 and Supplementary …

[HTML][HTML] Mediterraneibacter catenae SW178 sp. nov., an intestinal bacterium of feral chicken

S Wongkuna, S Ghimire, S Chankhamhaengdecha… - PeerJ, 2021 - peerj.com
A Gram-positive, coccobacillus, white raised and circular with an entire edge colony, and
obligately anaerobic bacterium, strain SW178 was isolated from the cecum content of feral …