User profiles for SG McInally
Shane Gregory McInallyWorcester Polytechnic Institute Verified email at wpi.edu Cited by 343 |
Microtubule organelles in Giardia
KD Hagen, SG McInally, ND Hilton, SC Dawson - Advances in parasitology, 2020 - Elsevier
Giardia lamblia is a widespread parasitic protist with a complex MT cytoskeleton that is critical
for motility, attachment, mitosis and cell division, and transitions between its two life cycle …
for motility, attachment, mitosis and cell division, and transitions between its two life cycle …
Robust and stable transcriptional repression in Giardia using CRISPRi
SG McInally, KD Hagen, C Nosala… - Molecular biology of …, 2019 - Am Soc Cell Biol
Giardia lamblia is a binucleate protistan parasite causing significant diarrheal disease
worldwide. An inability to target Cas9 to both nuclei, combined with the lack of nonhomologous …
worldwide. An inability to target Cas9 to both nuclei, combined with the lack of nonhomologous …
[HTML][HTML] Eight unique basal bodies in the multi-flagellated diplomonad Giardia lamblia
SG McInally, SC Dawson - Cilia, 2016 - Springer
Giardia lamblia is an intestinal parasitic protist that causes significant acute and chronic
diarrheal disease worldwide. Giardia belongs to the diplomonads, a group of protists in the …
diarrheal disease worldwide. Giardia belongs to the diplomonads, a group of protists in the …
Giardia Colonizes and Encysts in High-Density Foci in the Murine Small Intestine
NR Barash, C Nosala, JK Pham, SG McInally… - MSphere, 2017 - Am Soc Microbiol
Giardia lamblia is a highly prevalent yet understudied protistan parasite causing significant
diarrheal disease worldwide. Hosts ingest Giardia cysts from contaminated sources. In the …
diarrheal disease worldwide. Hosts ingest Giardia cysts from contaminated sources. In the …
Length-dependent disassembly maintains four different flagellar lengths in Giardia
With eight flagella of four different lengths, the parasitic protist Giardia is an ideal model to
evaluate flagellar assembly and length regulation. To determine how four different flagellar …
evaluate flagellar assembly and length regulation. To determine how four different flagellar …
[HTML][HTML] Harnessing the power of new genetic tools to illuminate Giardia biology and pathogenesis
KD Hagen, CJS Hart, SG McInally, SC Dawson - Genetics, 2024 - academic.oup.com
Giardia is a prevalent single-celled microaerophilic intestinal parasite causing diarrheal
disease and significantly impacting global health. Double diploid (essentially tetraploid) Giardia …
disease and significantly impacting global health. Double diploid (essentially tetraploid) Giardia …
Scaling of subcellular actin structures with cell length through decelerated growth
How cells tune the size of their subcellular parts to scale with cell size is a fundamental
question in cell biology. Until now, most studies on the size control of organelles and other …
question in cell biology. Until now, most studies on the size control of organelles and other …
Quantitative analysis of actin cable length in yeast
… Therefore, cable length is determined by a balance between these two simultaneous competing
effects (McInally et al., … This protocol was developed and used in a recent study (McInally …
effects (McInally et al., … This protocol was developed and used in a recent study (McInally …
[HTML][HTML] Length control emerges from cytoskeletal network geometry
Many cytoskeletal networks consist of individual filaments that are organized into elaborate
higher order structures. While it is appreciated that the size and architecture of these …
higher order structures. While it is appreciated that the size and architecture of these …
Affinity-purified Plasmodium tubulin provides a key reagent for antimalarial drug development
SG McInally, SC Dawson - Trends in Parasitology, 2022 - cell.com
Hirst et al. used a TOG-domain-based affinity-purification approach to reconstitute and define
the in vitro dynamics of blood-stage Plasmodium falciparum αβ-tubulin. This provides a key …
the in vitro dynamics of blood-stage Plasmodium falciparum αβ-tubulin. This provides a key …