Background We conducted a meta-analysis in nonmetastatic breast cancer patients treated
by neoadjuvant chemotherapy (NCT) to assess the clinical validity of circulating tumor cell (…

The 15th St. Gallen International Breast Cancer Conference 2017 in Vienna, Austria reviewed
substantial new evidence on loco-regional and systemic therapies for early breast cancer. …

Breast cancer risk is influenced by rare coding variants in susceptibility genes, such as
BRCA1, and many common, mostly non-coding variants. However, much of the genetic …

The prevalence of müllerian malformations is 1 in 200, or 0.5%. A third of the anomalies are
septate, a third bicornuate uteri, 10% arcuate uterus, 10% didelphis and unicornuate uterus, …

Progress has been made in the treatment of metastatic breast cancer in recent decades, but
very few therapies use patient or tumor-specific characteristics to tailor individualized …

Stratification of women according to their risk of breast cancer based on polygenic risk scores
(PRSs) could improve screening and prevention strategies. Our aim was to develop PRSs, …

Accumulating data suggest that metastatic dissemination often occurs early during tumour
formation, but the mechanisms of early metastatic spread have not yet been addressed. Here, …

Background We have previously developed and confirmed a pragmatic molecular classifier
for endometrial cancers; ProMisE (Proactive Molecular Risk Classifier for Endometrial …

Purpose: Although unequivocal evidence has shown the prognostic relevance of circulating
tumor cells (CTC) in the peripheral blood of patients with metastatic breast cancer, less …

Breast cancer susceptibility variants frequently show heterogeneity in associations by tumor
subtype 1 , 2 – 3 . To identify novel loci, we performed a genome-wide association study …