Radioactivity is known to induce tumors, chromosome lesions, and minisatellite length
mutations, but its effects on the DNA sequence have not previously been studied. A coastal …

Mitochondrial point heteroplasmy is a common event observed not only in patients with
mitochondrial diseases but also in healthy individuals. We here report a comprehensive …

Messenger RNA (mRNA) profiling in post-mortem human tissue might reveal information
about gene expression at the time point of death or close to it. When working with post-mortem …

Recently, several authors described the observation that RNA degradation does not correlate
with the postmortem interval (PMI), but rather with other parameters like environmental …

Recently in PNAS, Luo et al.(1) report the observation of heteroplasmic mixtures of
mitochondrial DNA (mtDNA) in the blood of three unrelated patients suffering from different …

The use of DNA methylation (DNAm) for chronological age determination has been widely
investigated within the last few years for its application within the field of forensic genetics. …

This paper presents an overview of the organisation and the results of the collaborative
exercises (CE) of the European DNA Profiling (EDNAP) Group’s mitochondrial DNA population …

Gene expression analyses based on messenger RNA (mRNA) profiling require accurate
data normalisation. When using endogenous reference genes, these have to be validated …

The maternal mode of mitochondrial DNA (mtDNA) inheritance is central to human genetics.
Recently, evidence for bi-parental inheritance of mtDNA was claimed for individuals of three …

A large number of short tandem repeat (STR) markers spanning the entire human X chromosome
have been described and established for use in forensic genetic testing. Due to their …