User profiles for Sabrina Simoncelli

Sabrina Simoncelli

Lecturer - Department of Chemistry & LCN - University College London
Verified email at ucl.ac.uk
Cited by 734

Quantitative single-molecule surface-enhanced Raman scattering by optothermal tuning of DNA origami-assembled plasmonic nanoantennas

S Simoncelli, EM Roller, P Urban, R Schreiber… - ACS …, 2016 - ACS Publications
DNA origami is a powerful approach for assembling plasmonic nanoparticle dimers and
Raman dyes with high yields and excellent positioning control. Here we show how optothermal-…

Nanoscale control of molecular self-assembly induced by plasmonic hot-electron dynamics

S Simoncelli, Y Li, E Cortés, SA Maier - ACS nano, 2018 - ACS Publications
Self-assembly processes allow designing and creating complex nanostructures using
molecules as building blocks and surfaces as scaffolds. This autonomous driven construction is …

[HTML][HTML] Machine learning for cluster analysis of localization microscopy data

DJ Williamson, GL Burn, S Simoncelli, J Griffié… - Nature …, 2020 - nature.com
Quantifying the extent to which points are clustered in single-molecule localization
microscopy data is vital to understanding the spatial relationships between molecules in the …

Imaging plasmon hybridization of Fano resonances via hot-electron-mediated absorption mapping

S Simoncelli, Y Li, E Cortés, SA Maier - Nano Letters, 2018 - ACS Publications
The inhibition of radiative losses in dark plasmon modes allows storing electromagnetic
energy more efficiently than in far-field excitable bright-plasmon modes. As such, processes …

[HTML][HTML] Synthesis, acid properties and catalysis by niobium oxide nanostructured materials

…, S Impellizzeri, C Fasciani, S Simoncelli… - Catalysis Science & …, 2014 - pubs.rsc.org
Several forms of niobium oxide were prepared, including nanostructured mesoporous
materials, and their acidity properties were comprehensively investigated and compared with …

Purinergic GPCR-integrin interactions drive pancreatic cancer cell invasion

…, J Gibson, A Samadi, HM Kocher, S Simoncelli… - Elife, 2023 - elifesciences.org
Pancreatic ductal adenocarcinoma (PDAC) continues to show no improvement in survival
rates. One aspect of PDAC is elevated ATP levels, pointing to the purinergic axis as a potential …

Monitoring plasmonic hot-carrier chemical reactions at the single particle level

S Simoncelli, EL Pensa, T Brick, J Gargiulo… - Faraday …, 2019 - pubs.rsc.org
Plasmon excitation in metal nanoparticles triggers the generation of highly energetic charge
carriers that, when properly manipulated and exploited, can mediate chemical reactions. …

[HTML][HTML] Quantitative super-resolution imaging for the analysis of GPCR oligomerization

…, E Tomas Bort, RP Grose, PJ McCormick, S Simoncelli - Biomolecules, 2021 - mdpi.com
G-protein coupled receptors (GPCRs) are known to form homo- and hetero- oligomers which
are considered critical to modulate their function. However, studying the existence and …

[PDF][PDF] Multi-color molecular visualization of signaling proteins reveals how C-terminal Src kinase nanoclusters regulate T cell receptor activation

S Simoncelli, J Griffié, DJ Williamson, J Bibby, C Bray… - Cell Reports, 2020 - cell.com
Elucidating the mechanisms that controlled T cell activation requires visualization of the spatial
organization of multiple proteins on the submicron scale. Here, we use stoichiometrically …

Excited state kinetics in crystalline solids: self-quenching in nanocrystals of 4, 4′-disubstituted benzophenone triplets occurs by a reductive quenching mechanism

G Kuzmanich, S Simoncelli, MN Gard… - Journal of the …, 2011 - ACS Publications
We report an efficient triplet state self-quenching mechanism in crystals of eight benzophenones,
which included the parent structure (1), six 4,4′-disubstituted compounds with NH 2 (2)…