Aggregation of the microtubule-associated protein Tau is a hallmark of Alzheimer’s disease
with Tau oligomers suspected as the most toxic agent. Tau is a client of the molecular …

Norovirus infection is the major cause of nonbacterial gastroenteritis in humans and has
been the subject of numerous studies investigating the virus’s biophysical properties and …

Intrinsically disordered proteins (IDPs) play important physiological, but also diseaserelated
roles. In order to understand the function and malfunction of proteins of this class, electron …

Metallamacrocylic tetraruthenium complexes were generated by treatment of 1,4‐divinylphenylene‐bridged
diruthenium complexes with functionalized 1,3‐benzene dicarboxylic acids …

Multivalent ligand–protein interactions are a key concept in biology mediating, for example,
signalling and adhesion. Multivalent ligands often have tremendously increased binding …

EPR distance determination in the nanometre region has become an important tool for
studying the structure and interaction of macromolecules. Arbitrary waveform generators (AWGs), …

A series of mononuclear σ-phenyl ruthenium complexes Ru(CO)Cl(C 6 H 4 -R)(P i Pr 3 ) 2 (R
= OMe, CH 3 , H, F, CF 3 ) were synthesized and analyzed with respect to their …

Multivalent carbohydrate–lectin interactions are a key concept in biological processes
mediating, for example, signaling and adhesion. Binding affinities of multivalent ligands often …

In recent years, the measurement of distance distributions in the nanometer range using
double electron-electron resonance (DEER), a pulsed electron paramagnetic resonance (EPR) …

This chapter summarizes the state of the art in electron paramagnetic resonance (EPR)
spectroscopy. It should give the reader an overview of the tremendous methodological …