Genetic analyses of diverse populations improves discovery for complex traits

…, CL Wassel, LR Wilkens, CA Winkler, S Yoneyama… - Nature, 2019 - nature.com
Genome-wide association studies (GWAS) have laid the foundation for investigations into the
biology of complex traits, drug development and clinical guidelines. However, the majority …

Genetic diversity turns a new PAGE in our understanding of complex traits

…, TA Thornton, CL Wassel, LR Wilkens, S Yoneyama… - BioRxiv, 2017 - biorxiv.org
Genome-wide association studies (GWAS) have laid the foundation for many downstream
investigations, including the biology of complex traits, drug development, and clinical …

The page study: how genetic diversity improves our understanding of the architecture of complex traits

…, CL Wassel, LR Wilkens, CA Winkler, S Yoneyama… - 2017 - europepmc.org
Genome-wide association studies (GWAS) have laid the foundation for investigations into
the biology of complex traits, drug development, and clinical guidelines. However, the …

Syntheses of cyclopentyl nucleoside (−)-neplanocin A through tetrazole-fragmentation from cyanophosphates

H Yoneyama, K Uemura, Y Usami, S Harusawa - Tetrahedron, 2018 - Elsevier
We recently reported a novel synthetic method for five-membered unsaturated cyclic
compounds from ketones involving cyanophosphates (CPs) under neutral conditions, in which …

[HTML][HTML] Outocomes of Second Unrelated Cord Blood Transplant for Relapse After First Allogeneic Transplant In Adult Patients with Progressive Acute Myeloid …

…, N Uchida, K Izutsu, A Wake, S Makino, A Yoneyama… - Blood, 2010 - Elsevier
Abstract 1295 Disease relapse following allogeneic hematopoietic stem cell transplant (allo-HSCT)
remains a major cause of treatment failure, often with a poor outcome. Some recent …

Fetal circulatory responses to maternal blood loss

…, G Ishikawa, T Ohshita, R Sawa, Y Yoneyama… - Gynecologic and …, 2001 - karger.com
We examined the fetal circulatory responses to maternal blood loss in pregnant women during
the third trimester. Seven healthy women with placenta previa and singleton pregnancies …

[HTML][HTML] Prospective weekly multiple viral monitoring in blood using multiplex PCR assay early after hematopoietic stem cell transplantation

…, N Uchida, K Izutsu, K Masuoka, A Wake, A Yoneyama… - Blood, 2011 - Elsevier
Abstract 1954 Backgrounds: Viral infections remain serious complications after hematopoietic
stem cell transplantation (HSCT), despite a remarkable progress of the prophylactic and …

[HTML][HTML] Graft-Versus-Host Disease Prophylaxis Using Tacrolimus+ Mycophenolate in Cord Blood Transplantation for Elderly; Impact of Mycophenolate Dosing

…, K Izutsu, K Masuoka, S Makino, A Yoneyama… - Blood, 2011 - Elsevier
Abstract 4563 Introduction: Cord blood transplantation with fludarabine-containing toxicity-reduced
conditioning (RT-CBT) has been widely applied to adult patients who have advanced …

Redox Regulation of the NFKB Signaling Pathway and Disease Control

…, S Sakurada, T Kato, A Yoneyama… - Oxidative Stress in …, 1997 - taylorfrancis.com
Oxygen plays complexed roles in the cell. While oxygen is indispensable for an aerobic cell
to obtain the essential chemical energy in the form of ATP, it is often transformed into highly …

[PDF][PDF] Phosphorylation of Npas4 by MAPK regulates reward-related gene expression and behaviors

Y Funahashi, A Ariza, R Emi, Y Xu, W Shan, K Suzuki… - Cell reports, 2019 - cell.com
Dopamine (DA) activates mitogen-activated protein kinase (MAPK) via protein kinase A (PKA)/Rap1
in medium spiny neurons (MSNs) expressing the dopamine D1 receptor (D1R) in …