Toxicity of silver nanoparticles (AgNPs) is supported by many observations in literature, but
no mechanism details have been proved yet. Here we confirm and quantify the toxic potential …

Neoantigen-based immunotherapies promise to improve patient outcomes over the current
standard of care. However, detecting these cancer-specific antigens is one of the significant …

Albumin is one of the most abundant plasma proteins and is heavily glycated in diabetes. In
this study, we have addressed whether variation in the albumin levels influence glycation of …

Worldwide efforts are currently trying to produce effective risk assessment models for orally
ingested nanoparticles. These tests should provide quantitative information on the …

Autoimmune disease results from the immune response against self-antigens, while cancer
develops when the immune system does not respond to malignant cells. Thus, for years, …

Interferon (IFN)-related DNA damage resistant signature (IRDS) genes are a subgroup of
interferon-stimulated genes (ISGs) found upregulated in different cancer types, which promotes …

Tumor antigens can emerge through multiple mechanisms, including translation of noncoding
genomic regions. This noncanonical category of tumor antigens has recently gained …

Developments in quantitative proteomics and use of data-independent acquisition (DIA)
methodology is enabling measurement of proteins of interest in biological samples. Currently, …

Interferon-induced transmembrane proteins IFITM1 and IFITM3 (IFITM1/3) play a role in
both RNA viral restriction and in human cancer progression. Using immunohistochemical …

Proteomics of human tissues and isolated cellular subpopulations create new opportunities
for therapy and monitoring of a patients’ treatment in the clinic. Important considerations in …