Increased Intensity Of PCR Testing Reduced COVID-19 Transmission Within Countries During The First Pandemic Wave: Study examines increased intensity of …

…, SN Amarasinghe, I Sivagnanam, S Fonseka… - Health …, 2021 - healthaffairs.org
Experts agree that reverse transcription–polymerase chain reaction (PCR) testing is critical
in controlling coronavirus disease 2019 (COVID-19), but decision makers disagree on how …

The role of p75NTR in cholinergic basal forebrain structure and function

…, F Alfonsi, BA Rumballe, S Fonseka… - Journal of …, 2014 - Soc Neuroscience
The role of the p75 neurotrophin receptor (p75 NTR ) in adult cholinergic basal forebrain (cBF)
neurons is unclear due to conflicting results from previous studies and to limitations of …

A robust method for particulate detection of a genetic tag for 3D electron microscopy

…, A Christopoulos, NS Bryce, ML Cagigas, S Fonseka… - Elife, 2021 - elifesciences.org
Genetic tags allow rapid localization of tagged proteins in cells and tissues. APEX, an
ascorbate peroxidase, has proven to be one of the most versatile and robust genetic tags for …

[HTML][HTML] Factors impacting sustained coverage in the context of donor transitions: experience from Sri Lanka

PN Perera, SN Amarasinghe, SH Fonseka… - Health Policy and …, 2024 - ncbi.nlm.nih.gov
Although not reliant on donor funding for health, the external assistance that Sri Lanka receives
contributes to the improvement of the health system and health outcomes. In this study, …

De novo macrocyclic peptides for inhibiting, stabilizing, and probing the function of the retromer endosomal trafficking complex

…, MD Healy, J Sacharz, SJ Norwood, S Fonseka… - Science …, 2021 - science.org
The retromer complex (Vps35-Vps26-Vps29) is essential for endosomal membrane trafficking
and signaling. Mutation of the retromer subunit Vps35 causes late-onset Parkinson’s …

Sri Lanka's COVID-19 response and maintaining health services: implications for future pandemics

…, KCS Dalpatadu, N Wisidagama, S Fonseka… - BMJ Global …, 2024 - gh.bmj.com
This study examines how Sri Lanka, a lower-middle income country, managed its COVID-19
response and maintained health services. It draws on an extensive document review, key …

A role for caveolar proteins in regulation of the circadian clock

S Fonseka, BD Weger, M Weger, N Martel, TE Hall… - bioRxiv, 2022 - biorxiv.org
Caveolae are specialized invaginations of the plasma membrane that are formed by the co-assembly
of caveolin integral membrane proteins and a cytoplasmic cavin coat complex. …

Measurement of uPAR and αvꞵ6 for early stage colorectal cancer diagnosis

S Fonseka - 2022 - figshare.mq.edu.au
Colorectal cancer (CRC), characterised by tumours of the colon, rectum and appendix, is the
3rd leading cause of cancer-related death worldwide. The survival rate is dependent on the …

APEX-gold: a genetically-encoded particulate marker for robust 3D electron microscopy

…, A Christopoulos, NS Bryce, ML Cagigas, S Fonseka… - bioRxiv, 2020 - biorxiv.org
Genetic tags allow rapid localization of tagged proteins in cells and tissues. APEX, an
ascorbate peroxidase, has proven to be one of the most versatile and robust genetic tags for …

[CITATION][C] Characterisation of the cavin proteins role in the circadian rhythm

S Fonseka - 2022 - espace.library.uq.edu.au
Caveolae are nanoscale size invaginations of the plasma membrane identified by their
unique flask-shape morphology. They are considered to play an important role in lipid …