A major challenge in neurobiology in the 21st century is to understand how the brain adapts
with experience. Activity-dependent gene expression is integral to the synaptic plasticity …

Here, we used RNA capture-seq to identify a large population of lncRNAs that are expressed
in the infralimbic prefrontal cortex of adult male mice in response to fear-related learning. …

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The RNA modification N 6 -methyladenosine (m 6 A) regulates the interaction between RNA
and various RNA binding proteins within the nucleus and other subcellular compartments …

We have identified a member of the growth arrest and DNA damage (Gadd45) protein family,
Gadd45γ, which is known to be critically involved in DNA repair, as a key player in the …

DNA forms conformational states beyond the right-handed double helix; however, the
functional relevance of these noncanonical structures in the brain remains unknown. Here we …

Long noncoding RNAs (lncRNAs) represent a multidimensional class of regulatory molecules
involved in many aspects of brain function. Emerging evidence indicates that lncRNAs are …

The conformational state of DNA fine-tunes the transcriptional rate and abundance of RNA.
Here we report that DNA G-quadruplex (G4-DNA) accumulates in neurons, in an experience-…

The RNA modification N 6 -methyladenosine (m 6 A) is critically involved in the regulation of
gene activity underlying experience-dependent plasticity, and is necessary for the functional …