User profiles for Sahand Hormoz
Sahand HormozHarvard University Verified email at hms.harvard.edu Cited by 2276 |
Synthetic recording and in situ readout of lineage information in single cells
Reconstructing the lineage relationships and dynamic event histories of individual cells
within their native spatial context is a long-standing challenge in biology. Many biological …
within their native spatial context is a long-standing challenge in biology. Many biological …
[PDF][PDF] Reconstructing the lineage histories and differentiation trajectories of individual cancer cells in myeloproliferative neoplasms
Some cancers originate from a single mutation event in a single cell. Blood cancers known
as myeloproliferative neoplasms (MPNs) are thought to originate when a driver mutation is …
as myeloproliferative neoplasms (MPNs) are thought to originate when a driver mutation is …
Direct observation of Kelvin waves excited by quantized vortex reconnection
Quantized vortices are key features of quantum fluids such as superfluid helium and Bose–Einstein
condensates. The reconnection of quantized vortices and subsequent emission of …
condensates. The reconnection of quantized vortices and subsequent emission of …
[PDF][PDF] An engineered CRISPR-Cas9 mouse line for simultaneous readout of lineage histories and gene expression profiles in single cells
Tracing the lineage history of cells is key to answering diverse and fundamental questions in
biology. Coupling of cell ancestry information with other molecular readouts represents an …
biology. Coupling of cell ancestry information with other molecular readouts represents an …
Potential singularity mechanism for the Euler equations
MP Brenner, S Hormoz, A Pumir - Physical Review Fluids, 2016 - APS
Singular solutions to the Euler equations could provide essential insight into the formation of
very small scales in highly turbulent flows. Previous attempts to find singular flow structures …
very small scales in highly turbulent flows. Previous attempts to find singular flow structures …
Terahertz quantum cascade lasers with copper metal-metal waveguides operating up to 178 K
We report terahertz quantum cascade lasers operating in pulsed mode at an emission frequency
of 3 THz and up to a maximum temperature of 178 K. The improvement in the maximum …
of 3 THz and up to a maximum temperature of 178 K. The improvement in the maximum …
[HTML][HTML] Probe-based bacterial single-cell RNA sequencing predicts toxin regulation
Clonal bacterial populations rely on transcriptional variation across individual cells to produce
specialized states that increase fitness. Understanding all cell states requires studying …
specialized states that increase fitness. Understanding all cell states requires studying …
Design principles for self-assembly with short-range interactions
S Hormoz, MP Brenner - Proceedings of the National …, 2011 - National Acad Sciences
Recent experimental advances have opened up the possibility of equilibrium self-assembly
of functionalized nanoblocks with a high degree of controllable specific interactions. Here, …
of functionalized nanoblocks with a high degree of controllable specific interactions. Here, …
Metabolic interactions between dynamic bacterial subpopulations
10.7554/eLife.33099.001 Individual microbial species are known to occupy distinct metabolic
niches within multi-species communities. However, it has remained largely unclear …
niches within multi-species communities. However, it has remained largely unclear …
[PDF][PDF] Inferring cell-state transition dynamics from lineage trees and endpoint single-cell measurements
As they proliferate, living cells undergo transitions between specific molecularly and
developmentally distinct states. Despite the functional centrality of these transitions in multicellular …
developmentally distinct states. Despite the functional centrality of these transitions in multicellular …