<p>This paper is a comprehensive review of the effects of bioactive polyphenolic compounds
commonly found in many fruits and vegetables on cancer. These include the pheniolic …

S-adenosylmethionine (SAM) and S-adenosylhomocysteine (SAH) link one-carbon metabolism
to methylation status. However, it is unknown whether regulation of SAM and SAH by …

Nutrition exerts considerable effects on health, and dietary interventions are commonly
used to treat diseases of metabolic aetiology. Although cancer has a substantial metabolic …

Nutrition and metabolism are known to influence chromatin biology and epigenetics through
post-translational modifications, yet how this interaction influences genomic architecture …

A metabolic health crisis is evident as cardiovascular diseases ( CVD ) remain the leading
cause of mortality in the United States. Effects of resistant starch type 4 ( RS 4), a prebiotic fiber…

Despite well-documented evidence for lifespan extension by methionine restriction (MR),
underlying mechanisms remain unknown. As methionine can alter S-adenosylmethionine (SAM…

Dietary methionine restriction (MR) extends life span across species via various intracellular
regulatory mechanisms. In rodents, MR induces resistance against adiposity, improves …

Objectives Dietary restriction of methionine (Met) and cysteine (Cys) delays the aging process
and aging-related diseases, improves glucose and fat metabolism and reduces oxidative …

Objective Identifying novel approaches to combat obesity is important to improve health span.
It was hypothesized that methionine restriction (MR) will induce weight loss in obese mice …

Decreasing the dietary intake of methionine exerts robust anti‐adiposity effects in rodents
but modest effects in humans. Since cysteine can be synthesized from methionine, animal …