User profiles for Sam Michael
Michael SamUniversity of Otago Verified email at otago.ac.nz Cited by 1778 |
The National COVID Cohort Collaborative (N3C): rationale, design, infrastructure, and deployment
…, N Qureshi, MG Kurilla, SG Michael… - Journal of the …, 2021 - academic.oup.com
Objective Coronavirus disease 2019 (COVID-19) poses societal challenges that require
expeditious data and knowledge sharing. Though organizational clinical data are abundant, …
expeditious data and knowledge sharing. Though organizational clinical data are abundant, …
Security analysis of integrated circuit camouflaging
Camouflaging is a layout-level technique that hampers an attacker from reverse engineering
by introducing, in one embodiment, dummy contacts into the layout. By using a mix of real …
by introducing, in one embodiment, dummy contacts into the layout. By using a mix of real …
High-throughput combinatorial screening identifies drugs that cooperate with ibrutinib to kill activated B-cell–like diffuse large B-cell lymphoma cells
…, DY Duveau, JK Jiang, S Michael… - Proceedings of the …, 2014 - National Acad Sciences
The clinical development of drug combinations is typically achieved through trial-and-error
or via insight gained through a detailed molecular understanding of dysregulated signaling …
or via insight gained through a detailed molecular understanding of dysregulated signaling …
Undiagnosed SARS-CoV-2 seropositivity during the first 6 months of the COVID-19 pandemic in the United States
…, JP Denson, S Messing, SG Michael… - Science Translational …, 2021 - science.org
Asymptomatic SARS-CoV-2 infection and delayed implementation of diagnostics have led
to poorly defined viral prevalence rates in the United States and elsewhere. To address this, …
to poorly defined viral prevalence rates in the United States and elsewhere. To address this, …
[PDF][PDF] Therapeutic targeting of ATR yields durable regressions in small cell lung cancers with high replication stress
Small cell neuroendocrine cancers (SCNCs) are recalcitrant cancers arising from diverse
primary sites that lack effective treatments. Using chemical genetic screens, we identified …
primary sites that lack effective treatments. Using chemical genetic screens, we identified …
The Tox21 robotic platform for the assessment of environmental chemicals–from vision to reality
MS Attene-Ramos, N Miller, R Huang, S Michael… - Drug discovery today, 2013 - Elsevier
Highlights • The Tox21 effort is to advance in vitro toxicological testing in the 21st century. •
Tox21 chemical library contains approximately 10,000 environmental chemicals. • A battery …
Tox21 chemical library contains approximately 10,000 environmental chemicals. • A battery …
[HTML][HTML] Suppression of the FOXM1 transcriptional programme via novel small molecule inhibition
…, C Lowe, D Matak-Vinković, S Michael… - Nature …, 2014 - nature.com
The transcription factor FOXM1 binds to sequence-specific motifs on DNA (C/TAAACA)
through its DNA-binding domain (DBD) and activates proliferation- and differentiation-associated …
through its DNA-binding domain (DBD) and activates proliferation- and differentiation-associated …
The public management of sport: Wicked problems, challenges and dilemmas
MP Sam - Public management review, 2009 - Taylor & Francis
This article proposes that sport policy problems exhibit the characteristics of ‘wicked problems’,
in that they are difficult to define/interpret, are based in competing/uncertain causes, and …
in that they are difficult to define/interpret, are based in competing/uncertain causes, and …
[HTML][HTML] Standardization of ELISA protocols for serosurveys of the SARS-CoV-2 pandemic using clinical and at-home blood sampling
…, G Gulten, S Messing, J Hicks, S Michael… - Nature …, 2021 - nature.com
The extent of SARS-CoV-2 infection throughout the United States population is currently
unknown. High quality serology is key to avoiding medically costly diagnostic errors, as well as …
unknown. High quality serology is key to avoiding medically costly diagnostic errors, as well as …
A robotic platform for quantitative high-throughput screening
S Michael, D Auld, C Klumpp, A Jadhav… - Assay and drug …, 2008 - liebertpub.com
High-throughput screening (HTS) is increasingly being adopted in academic institutions,
where the decoupling of screening and drug development has led to unique challenges, as …
where the decoupling of screening and drug development has led to unique challenges, as …