[HTML][HTML] The structural basis for regulation of the glutathione transporter Ycf1 by regulatory domain phosphorylation
NK Khandelwal, CR Millan, SI Zangari, S Avila… - Nature …, 2022 - nature.com
Yeast Cadmium Factor 1 (Ycf1) sequesters heavy metals and glutathione into the vacuole to
counter cell stress. Ycf1 belongs to the ATP binding cassette C-subfamily (ABCC) of …
counter cell stress. Ycf1 belongs to the ATP binding cassette C-subfamily (ABCC) of …
The Role of Conserved GRD Motif in the Allosteric Regulation of Ycf1 Transport Activity and Protein Function
S Zangari - 2021 - search.proquest.com
Multidrug resistance is a rising issue in the healthcare field and presents itself in bacteria,
fungi, and mammalian cells. Clinical isolates of multidrug resistant cells reveal an upregulation …
fungi, and mammalian cells. Clinical isolates of multidrug resistant cells reveal an upregulation …
[PDF][PDF] Biochemical and structural insight of regulation in yeast vacuolar ABC transporter Ycf1
NK Khandelwal, CR Millan, SI Zangari, S Avila… - Biophysical …, 2022 - cell.com
Yeast Cadmium Factor-1 (Ycf1) is a vacuolar membrane localized ATP Binding Cassette (ABC)
transporter belonging to the C-subfamily and plays a crucial role in cell survival during …
transporter belonging to the C-subfamily and plays a crucial role in cell survival during …
Bone remineralization of lytic lesions in multiple myeloma–The Arkansas experience
Multiple myeloma (MM) patients frequently present with extensive osteolytic bone lesions.
However, the impact of myeloma treatment on focal lytic lesion remineralization has not been …
However, the impact of myeloma treatment on focal lytic lesion remineralization has not been …
A 52-week multicenter retrospective real-world study on effectiveness and safety of dupilumab in children with atopic dermatitis aged from 6 to 11 years
Background: Dupilumab has been shown to be a safe and effective drug for the treatment of
atopic dermatitis (AD) in children from 6 months to 11 years in randomized clinical trials. Aim…
atopic dermatitis (AD) in children from 6 months to 11 years in randomized clinical trials. Aim…
[HTML][HTML] The impact of comprehensive air purification on patient duration of stay, discharge outcomes, and health care economics: A retrospective cohort study
SP Stawicki, S Wolfe, C Brisendine, S Eid, M Zangari… - Surgery, 2020 - Elsevier
Background Infectious airborne and surface pathogens constitute a substantial and poorly
explored source of patient subclinical illness and infections. With that in mind, a system of …
explored source of patient subclinical illness and infections. With that in mind, a system of …
Clinical implications of loss of bone marrow minimal residual disease negativity in multiple myeloma
…, E Tian, G Tricot, F van Rhee, M Zangari - Blood …, 2022 - ashpublications.org
Multiple myeloma (MM) patients frequently attain a bone marrow (BM) minimal residual
disease (MRD) negativity status in response to treatment. We identified 568 patients who …
disease (MRD) negativity status in response to treatment. We identified 568 patients who …
[HTML][HTML] Late relapsing multiple myeloma≥ 10 years after treatment on total therapy protocols are associated with good outcome
…, S Thanendrarajan, CD Schinke, G Tricot, M Zangari… - Blood, 2020 - Elsevier
Introduction Novel agents are incorporated into a backbone of multi-agent chemotherapy
and tandem transplantation in successive Total Therapy (TT) protocols for multiple myeloma (…
and tandem transplantation in successive Total Therapy (TT) protocols for multiple myeloma (…
[HTML][HTML] Concomitant Deletion of Short Arm (del 1p) and Amplification or Gain (1q21) of Chromosome 1 By Fluorescence in Situ Hybridization (FISH) Is Associated …
…, F Zhan, F van Rhee, JR Sawyer, E Tian, M Zangari - Blood, 2021 - Elsevier
Introduction- Chromosome 1 abnormalities in multiple myeloma (MM) are increasingly
recognized as high risk defined features. While there is robust data on 1q21 gain and …
recognized as high risk defined features. While there is robust data on 1q21 gain and …
The small satellites of Pluto as observed by New Horizons
…, CCC Tsang, HHB Throop, OL White, AM Zangari - Science, 2016 - science.org
INTRODUCTION The Pluto system is surprisingly complex, comprising six objects that orbit
their common center of mass in approximately a single plane and in nearly circular orbits. …
their common center of mass in approximately a single plane and in nearly circular orbits. …