Genetic and epigenetic events have been implicated in the downregulation of the cellular
antigen processing and presentation machinery (APM), which in turn, has been associated …

Emerging cancers are sculpted by neo-Darwinian selection for superior growth and survival
but minimal immunogenicity; consequently, metastatic cancers often evolve common …

Curcuphenol, a common component of the culinary spices, naturally found in marine invertebrates
and plants, has been identified as a novel candidate for reversing immune escape by …

Cell-based cancer immunotherapy has achieved significant advancements, providing a
source of hope for cancer patients. Notwithstanding the considerable progress in cell-based …

One of the primary obstacles in current cancer treatments lies in the extensive heterogeneity
of genetic and epigenetic changes that occur in each arising tumour. However, an …

For eons, turmeric and curcumin have been used as culinary spices and as traditional
medicines and as vogue dietary supplements for a growing list of disorders, including arthritis, …

Purpose of Review Chronic wounds are a tremendous burden on the healthcare system and
lead to significant patient morbidity and mortality. Normal cutaneous wound healing occurs …

Tuberculosis (TB) accounted for 1.5 million deaths in 2014, and new classes of anti-TB drugs
are required. We report a class of functionalized 1,8-disubstituted cyclam derivatives that …

Objective: Individuals with serious mental illnesses are overrepresented in all facets of the
legal system. State-level criminal histories of patients with serious mental illnesses were …

Purpose Emerging genetic tests such as genomic sequencing (GS) can generate a broad
range of benefits, but funding criteria only prioritize diagnosis and clinical management. There …