User profiles for Sameed Ahmed
Sameed AhmedQuantitative Scientist, Takeda Pharmaceuticals Verified email at takeda.com Cited by 109 |
Understanding sex differences in long-term blood pressure regulation: insights from experimental studies and computational modeling
S Ahmed, R Hu, J Leete… - American Journal of …, 2019 - journals.physiology.org
Sex differences in blood pressure and the prevalence of hypertension are found in humans
and animal models. Moreover, there has been a recent explosion of data concerning sex …
and animal models. Moreover, there has been a recent explosion of data concerning sex …
Sex-specific computational models for blood pressure regulation in the rat
In the past decades, substantial effort has been devoted to the development of computational
models of the cardiovascular system. Some of these models simulate blood pressure …
models of the cardiovascular system. Some of these models simulate blood pressure …
Guiding dose selection of monoclonal antibodies using a new parameter (AFTIR) for characterizing ligand binding systems
Guiding the dose selection for monoclonal antibody oncology drugs is often done using
methods for predicting the receptor occupancy of the drug in the tumor. In this manuscript, …
methods for predicting the receptor occupancy of the drug in the tumor. In this manuscript, …
[HTML][HTML] High order integration factor methods for systems with inhomogeneous boundary conditions
Due to the high order spatial derivatives and stiff reactions, severe temporal stability constraints
on the time step are generally required when developing numerical methods for solving …
on the time step are generally required when developing numerical methods for solving …
[PDF][PDF] Impact of sex and pathophysiology on optimal drug choice in hypertensive rats: quantitative insights for precision medicine
Less than half of all hypertensive patients receiving treatment are successful in normalizing
their blood pressure. Despite the complexity and heterogeneity of hypertension, the current …
their blood pressure. Despite the complexity and heterogeneity of hypertension, the current …
[PDF][PDF] Moment stability for nonlinear stochastic growth kinetics of breast cancer stem cells with time-delays
Solid tumors are heterogeneous in composition. Cancer stem cells (CSCs) are a highly
tumorigenic cell type found in developmentally diverse tumors that are believed to be resistant to …
tumorigenic cell type found in developmentally diverse tumors that are believed to be resistant to …
Stability analysis of mathematical models for nonlinear growth kinetics of breast cancer stem cells
Cancer stem cells are responsible for tumor survival and resurgence and are thus essential
in developing novel therapeutic strategies against cancer. Mathematical models can help …
in developing novel therapeutic strategies against cancer. Mathematical models can help …
Sex‐specific Computational Models for Blood Pressure Regulation in the Rat
S Ahmed, J Leete, FL Hernandez… - The FASEB …, 2019 - Wiley Online Library
Renal hemodynamics play a critical role in blood pressure regulation, while renal
autoregulatory mechanisms maintain kidney function for varying blood pressure. Computational …
autoregulatory mechanisms maintain kidney function for varying blood pressure. Computational …
[HTML][HTML] Integrative Cardiovascular Physiology and Pathophysiology: Understanding sex differences in long-term blood pressure regulation: insights from …
Sex differences in blood pressure and the prevalence of hypertension are found in humans
and animal models. Moreover, there has been a recent explosion of data concerning sex …
and animal models. Moreover, there has been a recent explosion of data concerning sex …
Is there a cost of virus resistance in marine cyanobacteria?
Owing to their abundance and diversity, it is generally perceived that viruses are important
for structuring microbial communities and regulating biogeochemical cycles. The ecological …
for structuring microbial communities and regulating biogeochemical cycles. The ecological …