User profiles for Sameed Siddiqui

Sameed Muneeb Siddiqui

Graduate Student, Massacussetts Institute of Techonology
Verified email at mit.edu
Cited by 780

[HTML][HTML] Discrete SARS-CoV-2 antibody titers track with functional humoral stability

YC Bartsch, S Fischinger, SM Siddiqui, Z Chen… - Nature …, 2021 - nature.com
Antibodies serve as biomarkers of infection, but if sustained can confer long-term immunity.
Yet, for most clinically approved vaccines, binding antibody titers only serve as a surrogate of …

[HTML][HTML] Deployable CRISPR-Cas13a diagnostic tools to detect and report Ebola and Lassa virus cases in real-time

KG Barnes, AE Lachenauer, A Nitido, S Siddiqui… - Nature …, 2020 - nature.com
Recent outbreaks of viral hemorrhagic fevers (VHFs), including Ebola virus disease (EVD)
and Lassa fever (LF), highlight the urgent need for sensitive, deployable tests to diagnose …

[PDF][PDF] Theta oscillations in the human medial temporal lobe during real-world ambulatory movement

…, P Schuette, TA Fields, ME Tran, SM Siddiqui… - Current Biology, 2017 - cell.com
The theta rhythm—a slow (6–12 Hz) oscillatory component of the local field potential—plays
a critical role in spatial navigation and memory by coordinating the activity of neuronal …

[HTML][HTML] Integrated sample inactivation, amplification, and Cas13-based detection of SARS-CoV-2

…, AC Stanton, CK Boehm, BA Petros, S Siddiqui… - BioRxiv, 2020 - ncbi.nlm.nih.gov
The COVID-19 pandemic has highlighted that new diagnostic technologies are essential for
controlling disease transmission. Here, we develop SHINE (SHERLOCK and HUDSON …

[HTML][HTML] Streamlined inactivation, amplification, and Cas13-based detection of SARS-CoV-2

…, AC Stanton, BA Petros, CK Boehm, S Siddiqui… - Nature …, 2020 - nature.com
The COVID-19 pandemic has highlighted that new diagnostic technologies are essential for
controlling disease transmission. Here, we develop SHINE (Streamlined Highlighting of …

[HTML][HTML] SARS-CoV-2 antibodies protect against reinfection for at least 6 months in a multicentre seroepidemiological workplace cohort

…, R Lowe, S Fischinger, M de St Aubin, SM Siddiqui… - PLoS …, 2022 - journals.plos.org
Identifying the potential for SARS-CoV-2 reinfection is crucial for understanding possible
long-term epidemic dynamics. We analysed longitudinal PCR and serological testing data from …

[HTML][HTML] Epidemiological and immunological features of obesity and SARS-CoV-2

EJ Nilles, SM Siddiqui, S Fischinger, YC Bartsch… - Viruses, 2021 - mdpi.com
Obesity is a key correlate of severe SARS-CoV-2 outcomes while the role of obesity on risk
of SARS-CoV-2 infection, symptom phenotype, and immune response remain poorly defined. …

Serological markers of SARS-CoV-2 reinfection

SM Siddiqui, KA Bowman, AL Zhu, S Fischinger… - Mbio, 2022 - Am Soc Microbiol
As public health guidelines throughout the world have relaxed in response to vaccination
campaigns against SARS-CoV-2, it is likely that SARS-CoV-2 will remain endemic, fueled by …

[HTML][HTML] The origins and future of sentinel: an early-warning system for pandemic preemption and response

…, JS Schieffelin, M Schreiber, MC Seck, S Siddiqui… - Viruses, 2021 - mdpi.com
While investigating a signal of adaptive evolution in humans at the gene LARGE, we
encountered an intriguing finding by Dr. Stefan Kunz that the gene plays a critical role in Lassa …

[HTML][HTML] Structural variation detection by proximity ligation from formalin-fixed, paraffin-embedded tumor tissue

…, PD Hartley, B Rice, M Blanchette, S Siddiqui… - The Journal of Molecular …, 2019 - Elsevier
The clinical management and therapy of many solid tumor malignancies depends on detection
of medically actionable or diagnostically relevant genetic variation. However, a principal …