User profiles for Sameer Salunkhe

Sameer Salunkhe

- Verified email at uthscsa.edu - Cited by 265

Sameer Salunkhe

- Verified email at ncra.tifr.res.in - Cited by 56

[HTML][HTML] Bloom helicase mediates formation of large single–stranded DNA loops during DNA end processing

C Xue, SJ Salunkhe, N Tomimatsu, AS Kawale… - Nature …, 2022 - nature.com
Bloom syndrome (BS) is associated with a profoundly increased cancer risk and is caused by
mutations in the Bloom helicase (BLM). BLM is involved in the nucleolytic processing of the …

[HTML][HTML] Cell-free chromatin from dying cancer cells integrate into genomes of bystander healthy cells to induce DNA damage and inflammation

…, K Pal, B Rane, A Shaikh, S Salunkhe… - Cell Death …, 2017 - nature.com
Bystander cells of the tumor microenvironment show evidence of DNA damage and inflammation
that can lead to their oncogenic transformation. Mediator (s) of cell–cell communication …

Exploring diffuse radio emission in galaxy clusters and groups with uGMRT and SKA

…, V Parekh, P Gupta, S Chatterjee, S Salunkhe… - Journal of Astrophysics …, 2023 - Springer
Diffuse radio emission has been detected in a considerable number of galaxy clusters and
groups, revealing the presence of pervasive cosmic magnetic fields, and of relativistic …

ERBB2 and KRAS alterations mediate response to EGFR inhibitors in early stage gallbladder cancer

…, B Dharavath, R Thorat, S Salunkhe… - … journal of cancer, 2019 - Wiley Online Library
The uncommonness of gallbladder cancer in the developed world has contributed to the
generally poor understanding of the disease. Our integrated analysis of whole exome …

[HTML][HTML] Metabolic rewiring in drug resistant cells exhibit higher OXPHOS and fatty acids as preferred major source to cellular energetics

S Salunkhe, SV Mishra, A Ghorai, A Hole… - … et Biophysica Acta (BBA …, 2020 - Elsevier
Alteration in metabolic repertoire is associated with resistance phenotype. Although a common
phenotype, not much efforts have been undertaken to design effective strategies to target …

Inhibition of SETMAR–H3K36me2–NHEJ repair axis in residual disease cells prevents glioblastoma recurrence

…, A Achareker, M Ketkar, D Sarkar, S Salunkhe… - Neuro …, 2020 - academic.oup.com
Background Residual disease of glioblastoma (GBM) causes recurrence. However, targeting
residual cells has failed, due to their inaccessibility and our lack of understanding of their …

[HTML][HTML] Up-regulation of the kinase gene SGK1 by progesterone activates the AP-1–NDRG1 axis in both PR-positive and-negative breast cancer cells

…, R Prasad, H Dhamne, K Karve, S Salunkhe… - Journal of Biological …, 2018 - ASBMB
Preoperative progesterone intervention has been shown to confer a survival benefit to breast
cancer patients independently of their progesterone receptor (PR) status. This observation …

Nuclear localization of p65 reverses therapy-induced senescence

S Salunkhe, SV Mishra, J Nair, S Shah… - Journal of Cell …, 2021 - journals.biologists.com
Senescence is the arrest of cell proliferation and is a tumor suppressor phenomenon. In a
previous study, we have shown that therapy-induced senescence of glioblastoma multiforme (…

Inhibition of novel GCN5–ATM axis restricts the onset of acquired drug resistance in leukemia

S Salunkhe, SV Mishra, J Nair, S Ghosh… - … journal of cancer, 2018 - Wiley Online Library
Leukemia is majorly treated by topoisomerase inhibitors that induce DNA double strand
breaks (DSB) resulting in cell death. Consequently, modulation of DSB repair pathway renders …

Deciphering the ultra-steep-spectrum diffuse radio sources discovered in the cool-core cluster Abell 980

S Salunkhe, S Paul, G Krishna, S Sonkamble… - Astronomy & …, 2022 - aanda.org
Clusters of galaxies are excellent laboratories for studying recurring nuclear activity in galactic
nuclei since their hot gaseous medium can vastly prolong the detectability of their radio …