The endoplasmic reticulum is primarily responsible for protein folding and maturation.
However, the organelle is subject to varied stress conditions from time to time, which lead to the …

Alpha-1-antitrypsin (AAT) is an acute phase secretory glycoprotein that inhibits neutrophil
proteases like elastase and is considered as the archetype of a family of structurally related …

Alpha1-antitrypsin (AAT) is one of the major circulating anti-protease whose levels in
circulation are raised during excessive amount of proteases, especially neutrophil elastase (NE) …

The biotechnological uses of algae and cyanobacteria have been widely discussed in the
context of climate change and consequent efforts to circularize economies, minimize carbon …

IRE1 is a transmembrane signalling protein that activates the unfolded protein response
under endoplasmic reticulum stress. IRE1 is endowed with kinase and endoribonuclease …

Two fission yeast mitotic activators, Cdc13 and Cdc25, have been shown to increase in
concentration in correlation with cell size, and have been proposed to thereby regulate cell size …

The yeast Bud31 protein, a Prp19 complex (NTC) member, aids spliceosome assembly and
thus promotes efficient pre-mRNA splicing. The bud31 null cells show mild budding …

Alzheimer’s disease (AD) is the most common form of dementia, generally affecting elderly
people in the age group of above 60–65 years. Amyloid deposition has been found to be a …

Aims Osmolytes are small organic molecules which play a significant role in maintaining
functional homeostasis of proteins under extreme hostile stresses. Any imbalance to cell …

Background Organic cation transporter 1 primarily governs the action of metformin in the liver.
There are considerable inter-individual variations in metformin response. In light of this, it …