Metabolic networks are interconnected and influence diverse cellular processes. The protein-metabolite
interactions that mediate these networks are frequently low affinity and …

The conserved coat protein complex II (COPII) mediates the initial steps of secretory protein
trafficking by assembling onto subdomains of the endoplasmic reticulum (ER) in two layers …

Length-dependent axonopathy of the corticospinal tract causes lower limb spasticity and is
characteristic of several neurological disorders, including hereditary spastic paraplegia (HSP…

Mitotic arrest deficient 1 (Mad1) plays a well-characterized role in the mitotic checkpoint.
However, interphase roles of Mad1 that do not impact mitotic checkpoint function remain largely …

Block copolymer micelles encapsulate water insoluble drugs by chemical and physical means,
and they may target therapeutics to their site of action in a passive or active way. In this …

… the SAM instrument suite and how the SAM experiments … areas, describe the SAM analytical
approach within the MSL … of the individual and integrated SAM instruments (Figs. 1, 2, and 3)…

Importance Guidelines for patients with atherosclerotic cardiovascular disease (ASCVD)
recommend intensive statin therapy and adding nonstatin therapy if low-density lipoprotein …

The goal of this study was to assess a solvent evaporation method for the encapsulation of
amphotericin B (AmB) in poly(ethylene oxide)-block-poly(N-hexyl stearate l-aspartamide) (…

… The Nilgiri Block in southern India exposes exhumed … Major lithologies in this block include
charnockite with or without … and accretion events in this block occurred at 2700–2500 Ma. …

… In addition, free carboxyl groups on the core-forming poly(L-aspartic acid) block provide …
-b-PLAA block copolymers with fatty acid side chains on the PLAA block and assessed the effect …