Intratumoral hypoxia causes the formation of dysfunctional blood vessels, which contribute
to tumor metastasis and reduce the efficacy of therapeutic treatments. Blood vessels are …

Angiogenesis plays an important role in hepatocellular carcinoma (HCC), the inhibition of
which is explored for cancer prevention and treatment. The dietary phytochemical …

Angiogenesis relies on the ability of endothelial cells (ECs) to migrate over the extracellular
matrix via integrin receptors to respond to an angiogenic stimulus. Of the two neuropilin (NRP…

For nearly two decades now, the RGD (Arg-Gly-Asp)-binding αvβ3-integrin has been a focus
of anti-angiogenic drug design. These inhibitors are well-tolerated, but have shown only …

Integrin β3 is seen as a key anti‐angiogenic target for cancer treatment due to its expression
on neovasculature, but the role it plays in the process is complex; whether it is pro‐ or anti‐…

Anti-angiogenic treatments against αvβ3-integrin fail to block tumour growth in the long term,
which suggests that the tumour vasculature escapes from angiogenesis inhibition through …

Rationale & Objective The KDIGO (Kidney Disease: Improving Global Outcomes) guideline
for chronic kidney disease (CKD) presented an international classification system that ranks …

… Author Contributions: Drs J. Miller and Atkinson had full access to all of the data in the
study and take responsibility for the integrity of the data and the accuracy of the data analysis. …

Objective To assess depression in children with chronic kidney disease and to determine
associations with patient characteristics, intellectual and educational levels, and health-related …

Objective To define glomerular filtration rate (GFR) decline, hypertension (HTN), and proteinuria
in subjects with autosomal recessive polycystic kidney disease (ARPKD) and compare …