Cerebral autoregulation (CA) is a critical process for the maintenance of cerebral blood flow
and oxygenation. Assessment of CA is frequently used for experimental research and in the …

Nicotinamide adenine dinucleotide (NAD + ) is modulated by conditions of metabolic stress
and has been reported to decline with aging in preclinical models, but human data are …

In 1959, Niels Lassen illustrated the cerebral autoregulation curve in the classic review article
entitled Cerebral Blood Flow and Oxygen Consumption in Man. This concept suggested a …

Chronic reductions in cerebral blood flow (CBF) and cerebrovascular reactivity to CO 2 are
risk factors for cerebrovascular disease. Higher aerobic fitness is associated with higher CBF …

Exercise is a uniquely effective and pluripotent medicine against several noncommunicable
diseases of westernised lifestyles, including protection against neurodegenerative disorders…

Regular exercise improves the age-related decline in cerebral blood flow (CBF) and is
associated with improved cognitive function; however, less is known about the direct relationship …

Methods Nine individuals completed three exercise interventions in randomised order.
Measures were recorded across 3 days with exercise performed on the middle day, as either:(1) …

The increasing number of older adults has seen a corresponding growth in those affected
by neurovascular diseases, including stroke and dementia. Since cures are currently …

We provide an updated review on the current understanding of breathing and sleep at high
altitude in humans. We conclude that: (1) progressive changes in pH initiated by the …

Cerebral autoregulation (CA) refers to the control of cerebral tissue blood flow (CBF) in
response to changes in perfusion pressure. Due to the challenges of measuring intracranial …