Evaluating totipotency using criteria of increasing stringency

…, M El Bakkali, I Talon, N De Geest, P Kumar, SK To… - Nature cell …, 2021 - nature.com
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[HTML][HTML] Integrated multi-omics reveal polycomb repressive complex 2 restricts human trophoblast induction

…, SSFA van Knippenberg, L Biggins, SK To… - Nature cell …, 2022 - nature.com
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Defining totipotency using criteria of increasing stringency

…, M El Bakkali, I Talon, N De Geest, P Kumar, SK To… - biorxiv, 2020 - biorxiv.org
… all the differentiated cells that build the conceptus, yet how to capture this property in vitro …
to define totipotency. We illustrate how distinct criteria of increasing stringency can be used to

[HTML][HTML] Lysosomal pathways and autophagy distinctively control endothelial cell behavior to affect tumor vasculature

MB Schaaf, D Houbaert, O Meçe, SK To… - Frontiers in …, 2019 - frontiersin.org
… of main pro-angiogenic cascades to “starve” the tumor. … inhibitory effects of therapy to reignite
neovascularization and promote … to restrain cancer cell invasion and dissemination due to

Spatially Self‐Organized Three‐Dimensional Neural Concentroid as a Novel Reductionist Humanized Model to Study Neurovascular Development

YC Chai, SK To, S Simorgh, S Zaunz, YL Zhu… - Advanced …, 2024 - Wiley Online Library
Although human pluripotent stem cell (PSC)‐derived brain organoids have enabled researchers
to gain insight into human brain development and disease, these organoids contain …

Inferring regulators of cell identity in the human adult pancreas

L Vanheer, F Fantuzzi, SK To, A Schiavo… - NAR Genomics and …, 2023 - academic.oup.com
Cellular identity during development is under the control of transcription factors that form
gene regulatory networks. However, the transcription factors and gene regulatory networks …

Predicting the Key Regulators of Cell Identity in Human Adult Pancreas

L Vanheer, F Fantuzzi, SK To, AA Schiavo… - bioRxiv, 2020 - biorxiv.org
… can improve the power of scRNA-seq analyses to create a comprehensive human adult
pancreas cell atlas. We set out to analyze and integrate five publicly available datasets covering …

Evaluation of Stem-Cell Embryo Models by Integration with a Human Embryo Single-Cell Transcriptome Atlas

SK To, B Balaton, V Pasque - Embryo Models In Vitro: Methods and …, 2023 - Springer
… Finally, we aim to estimate how many PCs to include for our analysis by plotting … to what
extent each PC is able to explain the variation or heterogeneity of the data. If the PC is able to

Detection and accuracy rates of dogs trained to find scats of San Joaquin kit foxes (Vulpes macrotis mutica)

DA Smith, K Ralls, A Hurt, B Adams… - Animal Conservation …, 2003 - cambridge.org
… the hole of the block containing a kit fox scat, we … to associate the scent of kit fox scats with
its reward, we conditioned the dog to indicate that it had found a kit fox scat by sitting next to

Habitat evaluation using GIS: a case study applied to the San Joaquin kit fox

R Gerrard, P Stine, R Church, M Gilpin - Landscape and Urban Planning, 2001 - Elsevier
… There has yet been no attempt to convert much of this field … and visibility of the imperiled kit
fox and increasing trends … California to derive a small-cell GIS raster of habitat value for the kit