User profiles for Sander de Kivit
 | Sander de KivitSenior Postdoctoral Researcher, Leiden University Medical Center Verified email at lumc.nl Cited by 1443 |
[HTML][HTML] Regulation of intestinal immune responses through TLR activation: implications for pro-and prebiotics
S De Kivit, MC Tobin, CB Forsyth… - Frontiers in …, 2014 - frontiersin.org
The intestinal mucosa is constantly facing a high load of antigens including bacterial
antigens derived from the microbiota and food. Despite this, the immune cells present in the …
antigens derived from the microbiota and food. Despite this, the immune cells present in the …
Galectin‐9 induced by dietary synbiotics is involved in suppression of allergic symptoms in mice and humans
S de Kivit, E Saeland, AD Kraneveld, HJG van de Kant… - Allergy, 2012 - Wiley Online Library
Background: Prebiotic galacto‐ and fructo‐oligosaccharides (sc GOS /lc FOS ) resembling
non‐digestible oligosaccharides in human milk reduce the development of atopic disorders. …
non‐digestible oligosaccharides in human milk reduce the development of atopic disorders. …
[HTML][HTML] Functional Heterogeneity of CD4+ Tumor-Infiltrating Lymphocytes With a Resident Memory Phenotype in NSCLC
…, H Blaauwgeers, M Mensink, S De Kivit… - Frontiers in …, 2018 - frontiersin.org
Resident memory T cells (T RM ) inhabit peripheral tissues and are critical for protection
against localized infections. Recently, it has become evident that CD103 + T RM are not only …
against localized infections. Recently, it has become evident that CD103 + T RM are not only …
[PDF][PDF] Proteomic analyses of human regulatory T cells reveal adaptations in signaling pathways that protect cellular identity
To obtain a molecular definition of regulatory T (Treg) cell identity, we performed proteomics
and transcriptomics on various populations of human regulatory and conventional CD4 + T (…
and transcriptomics on various populations of human regulatory and conventional CD4 + T (…
Intestinal epithelium-derived galectin-9 is involved in the immunomodulating effects of nondigestible oligosaccharides
Dietary intervention using nondigestible oligosaccharides, short-chain galacto-oligosaccharides
(scGOS)/long-chain fructo-oligosaccharides (lcFOS), in combination with …
(scGOS)/long-chain fructo-oligosaccharides (lcFOS), in combination with …
Glycan recognition at the interface of the intestinal immune system: target for immune modulation via dietary components
The intestinal mucosa is constantly exposed to the luminal content, which includes micro-organisms
and dietary components. Prebiotic non-digestible oligosaccharides may be …
and dietary components. Prebiotic non-digestible oligosaccharides may be …
Oral tolerance induction by partially hydrolyzed whey protein in mice is associated with enhanced numbers of Foxp3+ regulatory T‐cells in the mesenteric lymph …
BCAM van Esch, B Schouten, S de Kivit… - Pediatric Allergy and …, 2011 - Wiley Online Library
To cite this article: van Esch BCAM, Schouten B, de Kivit S, Hofman GA, Knippels LMJ,
Willemsen LEM, Garssen J. Oral tolerance induction by partially hydrolyzed whey protein in mice …
Willemsen LEM, Garssen J. Oral tolerance induction by partially hydrolyzed whey protein in mice …
[PDF][PDF] Lymph node stromal cells generate antigen-specific regulatory T cells and control autoreactive T and B cell responses
…, CG de Graça, ED Keuning, JJ Koning, S de Kivit… - Cell reports, 2020 - cell.com
Within lymph nodes (LNs), T follicular helper (T FH ) cells help B cells to produce antibodies,
which can either be protective or autoreactive. Here, we demonstrate that murine LN …
which can either be protective or autoreactive. Here, we demonstrate that murine LN …
Stable human regulatory T cells switch to glycolysis following TNF receptor 2 costimulation
S de Kivit, M Mensink, AT Hoekstra, I Berlin… - Nature …, 2020 - nature.com
Following activation, conventional T (T conv ) cells undergo an mTOR-driven glycolytic
switch. Regulatory T (T reg ) cells reportedly repress the mTOR pathway and avoid glycolysis. …
switch. Regulatory T (T reg ) cells reportedly repress the mTOR pathway and avoid glycolysis. …
Apical TLR ligation of intestinal epithelial cells drives a Th1-polarized regulatory or inflammatory type effector response in vitro
S de Kivit, E van Hoffen, N Korthagen, J Garssen… - Immunobiology, 2011 - Elsevier
Intestinal epithelial cells (IEC) separate the mucosal immune system from the external milieu.
Under inflammatory conditions, Toll-like receptor (TLR) expression by IEC is increased. In …
Under inflammatory conditions, Toll-like receptor (TLR) expression by IEC is increased. In …