Tau seed amplification assays (SAAs) directly measure the seeding activity of tau and would
therefore be ideal biomarkers for clinical trials targeting seeding-competent tau in Alzheimer…

In Alzheimer disease, Tau pathology is thought to propagate from cell to cell throughout
interconnected brain areas. However, the forms of Tau released into the brain interstitial fluid (ISF…

One of the main pillars of the Physical Internet (PI) is cooperation. One possible form of
cooperation in freight transportation is bundling. As soon as bundling is in focus, we have to think …

Plant communities in natural ecosystems are changing and species are being lost due to
anthropogenic impacts including global warming and increasing nitrogen (N) deposition. We …

Mobile genetic elements have significantly shaped our genomic landscape. LINE-1
retroelements are the only autonomously active elements left in the human genome. Since new …

Hybrid metaheuristics for solving hard combinatorial optimization problems have been
intensively studied over the last few decades. This thesis considers such a hybridization of …

Objectives: In many countries including the United Kingdom, hearing aids are a first line of
audiologic intervention for many people with tinnitus and aidable hearing loss. Nevertheless, …

In the face of finite resources, allocations of research and health-care funding are dependent
upon high-quality evidence. Historically, tinnitus has been the poor cousin of hearing …

Fresh and SO 2 -poisoned Cu-SSZ-13 selective catalytic reduction (SCR) catalysts were
studied using near-ambient pressure X-ray photoelectron spectroscopy (NAP-XPS) in the …

This article examines the manner in which some new methodologies and novel concepts
have contributed to our understanding of how pulmonary surfactant reduces alveolar surface …