User profiles for Sandra J. Kuhlman

Sandra Kuhlman

Associate Professor, University at Buffalo
Verified email at buffalo.edu
Cited by 3913

Experience and activity-dependent maturation of perisomatic GABAergic innervation in primary visual cortex during a postnatal critical period

…, H Higashiyama, GW Knott, SJ Kuhlman… - Journal of …, 2004 - Soc Neuroscience
The neocortical GABAergic network consists of diverse interneuron cell types that display
distinct physiological properties and target their innervations to subcellular compartments of …

A disinhibitory microcircuit initiates critical-period plasticity in the visual cortex

SJ Kuhlman, ND Olivas, E Tring, T Ikrar, X Xu… - Nature, 2013 - nature.com
Early sensory experience instructs the maturation of neural circuitry in the cortex 1 , 2 . This
has been studied extensively in the primary visual cortex, in which loss of vision to one eye …

The biological clock nucleus: a multiphasic oscillator network regulated by light

JE Quintero, SJ Kuhlman… - Journal of …, 2003 - Soc Neuroscience
The circadian clock nucleus of the mammalian brain is composed of thousands of oscillator
neurons, each driven by the cell-autonomous action of a defined set of circadian clock genes…

[PDF][PDF] Response features of parvalbumin-expressing interneurons suggest precise roles for subtypes of inhibition in visual cortex

CA Runyan, J Schummers, A Van Wart, SJ Kuhlman… - Neuron, 2010 - cell.com
Inhibitory interneurons in the cerebral cortex include a vast array of subtypes, varying in
their molecular signatures, electrophysiological properties, and connectivity patterns. This …

Activity-dependent PSA expression regulates inhibitory maturation and onset of critical period plasticity

G Di Cristo, B Chattopadhyaya, SJ Kuhlman, Y Fu… - Nature …, 2007 - nature.com
Functional maturation of GABAergic innervation in the developing visual cortex is regulated
by neural activity and sensory inputs and in turn influences the critical period of ocular …

[HTML][HTML] High-resolution labeling and functional manipulation of specific neuron types in mouse brain by Cre-activated viral gene expression

SJ Kuhlman, ZJ Huang - PloS one, 2008 - journals.plos.org
We describe a method that combines Cre-recombinase knockin mice and viral-mediated
gene transfer to genetically label and functionally manipulate specific neuron types in the …

Phase resetting light pulses induce Per1 and persistent spike activity in a subpopulation of biological clock neurons

SJ Kuhlman, R Silver, J Le Sauter… - Journal of …, 2003 - Soc Neuroscience
The endogenous circadian clock of the mammalian suprachiasmatic nucleus (SCN) can be
reset by light to synchronize the biological clock of the brain with the external environment. …

Rhythmic regulation of membrane potential and potassium current persists in SCN neurons in the absence of environmental input

SJ Kuhlman, DG McMahon - European Journal of …, 2004 - Wiley Online Library
Neurons of the mammalian suprachiasmatic nucleus (SCN) generate self‐sustained rhythms
of action potential frequency having a period of approximately 24 h. It is generally believed …

Fast-spiking interneurons have an initial orientation bias that is lost with vision

SJ Kuhlman, E Tring, JT Trachtenberg - Nature neuroscience, 2011 - nature.com
We found that in mice, following eye opening, fast-spiking, parvalbumin-positive GABAergic
interneurons had well-defined orientation tuning preferences and that subsequent visual …

Introduction to chronobiology

SJ Kuhlman, LM Craig, JF Duffy - Cold Spring Harbor …, 2018 - cshperspectives.cshlp.org
A diverse range of species, from cyanobacteria to humans, evolved endogenous biological
clocks that allow for the anticipation of daily variations in light and temperature. The ability to …