User profiles for Sandra J. Kuhlman
Sandra KuhlmanAssociate Professor, University at Buffalo Verified email at buffalo.edu Cited by 3913 |
Experience and activity-dependent maturation of perisomatic GABAergic innervation in primary visual cortex during a postnatal critical period
…, H Higashiyama, GW Knott, SJ Kuhlman… - Journal of …, 2004 - Soc Neuroscience
The neocortical GABAergic network consists of diverse interneuron cell types that display
distinct physiological properties and target their innervations to subcellular compartments of …
distinct physiological properties and target their innervations to subcellular compartments of …
A disinhibitory microcircuit initiates critical-period plasticity in the visual cortex
Early sensory experience instructs the maturation of neural circuitry in the cortex 1 , 2 . This
has been studied extensively in the primary visual cortex, in which loss of vision to one eye …
has been studied extensively in the primary visual cortex, in which loss of vision to one eye …
The biological clock nucleus: a multiphasic oscillator network regulated by light
JE Quintero, SJ Kuhlman… - Journal of …, 2003 - Soc Neuroscience
The circadian clock nucleus of the mammalian brain is composed of thousands of oscillator
neurons, each driven by the cell-autonomous action of a defined set of circadian clock genes…
neurons, each driven by the cell-autonomous action of a defined set of circadian clock genes…
[PDF][PDF] Response features of parvalbumin-expressing interneurons suggest precise roles for subtypes of inhibition in visual cortex
Inhibitory interneurons in the cerebral cortex include a vast array of subtypes, varying in
their molecular signatures, electrophysiological properties, and connectivity patterns. This …
their molecular signatures, electrophysiological properties, and connectivity patterns. This …
Activity-dependent PSA expression regulates inhibitory maturation and onset of critical period plasticity
Functional maturation of GABAergic innervation in the developing visual cortex is regulated
by neural activity and sensory inputs and in turn influences the critical period of ocular …
by neural activity and sensory inputs and in turn influences the critical period of ocular …
[HTML][HTML] High-resolution labeling and functional manipulation of specific neuron types in mouse brain by Cre-activated viral gene expression
SJ Kuhlman, ZJ Huang - PloS one, 2008 - journals.plos.org
We describe a method that combines Cre-recombinase knockin mice and viral-mediated
gene transfer to genetically label and functionally manipulate specific neuron types in the …
gene transfer to genetically label and functionally manipulate specific neuron types in the …
Phase resetting light pulses induce Per1 and persistent spike activity in a subpopulation of biological clock neurons
SJ Kuhlman, R Silver, J Le Sauter… - Journal of …, 2003 - Soc Neuroscience
The endogenous circadian clock of the mammalian suprachiasmatic nucleus (SCN) can be
reset by light to synchronize the biological clock of the brain with the external environment. …
reset by light to synchronize the biological clock of the brain with the external environment. …
Rhythmic regulation of membrane potential and potassium current persists in SCN neurons in the absence of environmental input
SJ Kuhlman, DG McMahon - European Journal of …, 2004 - Wiley Online Library
Neurons of the mammalian suprachiasmatic nucleus (SCN) generate self‐sustained rhythms
of action potential frequency having a period of approximately 24 h. It is generally believed …
of action potential frequency having a period of approximately 24 h. It is generally believed …
Fast-spiking interneurons have an initial orientation bias that is lost with vision
We found that in mice, following eye opening, fast-spiking, parvalbumin-positive GABAergic
interneurons had well-defined orientation tuning preferences and that subsequent visual …
interneurons had well-defined orientation tuning preferences and that subsequent visual …
Introduction to chronobiology
SJ Kuhlman, LM Craig, JF Duffy - Cold Spring Harbor …, 2018 - cshperspectives.cshlp.org
A diverse range of species, from cyanobacteria to humans, evolved endogenous biological
clocks that allow for the anticipation of daily variations in light and temperature. The ability to …
clocks that allow for the anticipation of daily variations in light and temperature. The ability to …